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RECAPACITA 项目:对西班牙一组具有严重精神障碍和法律能力改变的人进行临床、神经心理学和功能特征描述。

The RECAPACITA project: Description of the clinical, neuropsychological and functional profile of a sample of people with severe mental disorder and legal capacity modification in Spain.

机构信息

Parc Sanitari Sant Joan de Déu, Barcelona, Spain; Etiopathogenesis and treatment of severe mental disorders (MERITT), Sant Joan de Déu Research Institute, Sant Joan de Déu Foundation, Barcelona, Spain; Department of Social Psychology and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain.

Department of Social Psychology and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain; Group of Invariance Studies for the Measurement and Analysis of Change in the Social and Health Environments (GEIMAC), Institute of Neurosciences (UBNeuro), University of Barcelona, 08035 Barcelona, Spain.

出版信息

Int J Law Psychiatry. 2023 May-Jun;88:101874. doi: 10.1016/j.ijlp.2023.101874. Epub 2023 Mar 22.

Abstract

UNLABELLED

Severe mental disorder (SMD) includes people with long-term mental disorders, disability and social dysfunction. The mental capacity evaluation of the people has been a key aspect in legislative systems around the world and different proposals have been made. In countries like Spain, until 2021, the mental capacity of individuals was assessed by means of legal proceedings. In the last years, there has been a notable increase in the number of claims for legal incapacity, but no data are available on the total number of persons with CM, neither on the specific pathologies, or clinical and cognitive profiles. In view of the total absence of data on the profile of people with SMD and modification of capacity, the RECAPACITA study was born. This study includes patients with SMD and CM, as well as those without CM, with the aim to describe exhaustively their clinical, neuropsychological and functional profile of people with SMD and CM, as well as obtaining a basic description of the social environment.

OBJECTIVES

To describe CM in SMD, to identify clinical diagnoses, clinical severity and neuropsychological deterioration.

METHODS

Cross-sectional descriptive study. 77 adult patients with SMD and CM, inpatients from the mental health sector of the Parc Sanitari Sant Joan de Déu (Spain), outpatients linked to the community rehabilitation services (CRS), and penitentiary inmates. CM, sociodemographic, clinical, functional and neuropsychological data are collected.

RESULTS

In the sample, 59.5% present total CM. 74.7% are men (mean: 52.5 years). 87,0% have a diagnosis of schizophrenia. The estimated premorbid IQ is 91.4. The Global Assessment of Functioning (GAF) had a mean of 50.5, the "Clinical Global Impression Scale" (CGI) was 4.6 and Scale Unawareness of Mental Disorders (SUMD) was 9.28. The cognitive results shows a profile with slow proceeding speed (mean scale score: 6.6), good working memory (mean SC: 8.3) and adequate verbal comprehension (mean SC: 7.3). In memory, coding is altered (Pz: -1.9), and long-term spontaneous recall (Pz: -2.3). In abstract reasoning, a slight alteration is obtained (Mean SC: 6), as well as in semantic fluency (Mean SC: 6.3), phonological (Mean SC: 5.9), and inhibitory capacity (Mean SC: 5.7).

CONCLUSIONS

Most of the sample are men with schizophrenia, with a total MC assumed by a tutelary foundation. They show a moderate alteration in global functioning and clinical global impression, with partial awareness of the disease. They present dysexecutive mild cognitive impairment, with poor memory coding and free retrieval capacity, and a normal IQ, adequate verbal comprehension and working memory. This study is the first to present objective data on the psychiatric, functional and cognitive status of a group of patients with CM. Such research could be a good starting point to address a topic of great interest from the health, social and legal point of view of the CM processes of people with SMD.

摘要

目的

描述严重精神障碍(SMD)患者的认知障碍(CM)情况,识别临床诊断、临床严重程度和神经心理学恶化。

方法

这是一项横断面描述性研究。纳入了来自西班牙圣琼德乌精神病院心理健康科的 77 名 SMD 伴 CM 住院患者、社区康复服务(CRS)的门诊患者以及监狱囚犯。收集了 CM 相关的社会人口学、临床、功能和神经心理学数据。

结果

在样本中,59.5%的患者存在完全性 CM。74.7%的患者为男性(平均年龄 52.5 岁)。87.0%的患者诊断为精神分裂症。估计的病前智商为 91.4。总体功能评估(GAF)得分为 50.5,“临床总体印象量表”(CGI)得分为 4.6,“精神障碍自知力评定量表”(SUMD)得分为 9.28。认知结果显示出进行速度较慢的特征(平均量表得分为 6.6),良好的工作记忆(平均量表得分为 8.3)和适当的言语理解(平均量表得分为 7.3)。在记忆方面,编码能力受损(Pz:-1.9),长时自发回忆受损(Pz:-2.3)。在抽象推理方面,轻度受损(平均量表得分为 6),语义流畅性(平均量表得分为 6.3)、语音流畅性(平均量表得分为 5.9)和抑制能力(平均量表得分为 5.7)也受损。

结论

大多数患者为男性,患有精神分裂症,存在由监护机构认定的全面认知障碍。他们在总体功能和临床总体印象方面表现出中度障碍,对疾病有部分自知力。他们表现出执行功能轻度认知障碍,记忆编码和自由检索能力较差,智商正常,言语理解和工作记忆能力尚可。这项研究首次提供了一组伴有 CM 的 SMD 患者的精神病学、功能和认知状况的客观数据。此类研究可能是从健康、社会和法律角度出发,解决 SMD 患者 CM 过程这一热点话题的良好起点。

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