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镉与高血压

Cadmium and hypertension.

作者信息

Spieker C, Zidek W, Zumkley H

机构信息

University Hospital, Münster, FRG.

出版信息

Nephron. 1987;47 Suppl 1:34-6. doi: 10.1159/000184550.

DOI:10.1159/000184550
PMID:3696347
Abstract

Cadmium, an environmental trace metal, has been implicated as a possible factor in human hypertension. Although the epidemiological studies on humans exposed to cadmium are biased by certain additional factors, more detailed information is available from animal studies and in vitro experiments. The results demonstrate that cadmium influences the vasopressor-induced reactivity and the stress strain characteristics of the blood vessel wall. Thus, it is conceivable that cadmium might contribute to the elevation of blood pressure. But still more convincing data are necessary to clarify the link between cadmium exposure and the development of human hypertension.

摘要

镉是一种环境痕量金属,被认为可能是导致人类高血压的一个因素。尽管针对接触镉的人群开展的流行病学研究受到某些其他因素的影响存在偏差,但动物研究和体外实验能提供更详细的信息。结果表明,镉会影响血管升压素诱导的反应性以及血管壁的应力应变特性。因此,可以想象镉可能会导致血压升高。但仍需要更有说服力的数据来阐明镉暴露与人类高血压发展之间的联系。

相似文献

1
Cadmium and hypertension.镉与高血压
Nephron. 1987;47 Suppl 1:34-6. doi: 10.1159/000184550.
2
[Cadmium toxicity. Cadmium and hypertension].
Pol Arch Med Wewn. 2004 Feb;111(2):243-9.
3
[Correlation of blood pressure and cadmium and lead content of the hair in nonsmoking males].[非吸烟男性血压与头发中镉和铅含量的相关性]
Zentralbl Hyg Umweltmed. 1989 Jun;188(3-4):240-53.
4
Role of cadmium in human and experimental hypertension.镉在人类及实验性高血压中的作用。
J Air Pollut Control Assoc. 1972 Apr;22(4):267-70. doi: 10.1080/00022470.1972.10469637.
5
[Health effects of occupational exposure to cadmium and its compounds and proposed preventive measures].
Med Pr. 1985;36(4):265-72.
6
Cadmium-induced hypertension in rats.镉诱导的大鼠高血压
Pharmacology. 1989;38(4):226-34. doi: 10.1159/000138541.
7
[Morphofunctional characteristics of cadmium-induced arterial hypertension].[镉诱导的动脉高血压的形态功能特征]
Biull Eksp Biol Med. 1991 Apr;111(4):420-3.
8
Atherosclerosis and hypertension induction by lead and cadmium ions: an effect prevented by calcium ion.铅离子和镉离子诱导动脉粥样硬化和高血压:钙离子可预防此效应。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6494-8. doi: 10.1073/pnas.78.10.6494.
9
Prevalence of hypertension among cadmium-exposed workers.镉暴露工人中高血压的患病率。
Arch Environ Health. 1985 May-Jun;40(3):185-90. doi: 10.1080/00039896.1985.10545915.
10
Some biochemical aspects of cadmium toxicology.
J Occup Med. 1975 Mar;17(3):189-95.

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Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table.接触重金属和元素周期表中其他化学元素所产生的临床和法医体征。
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