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[T- and B-lymphocytes in patients with chronic renal failure and in recipients of cadaveric allokidneys during the immediate posttransplant period].

作者信息

Dzerzhinskaia I I

出版信息

Biull Eksp Biol Med. 1979 Feb;87(2):174-6.

PMID:369635
Abstract

Investigations of the thymus-dependent and thymus-independent lymphocytes populations of patients with chronic renal failure showed the activity of the T-lymphocytes system to be depressed in these cases. Both the lymphocyte populations took part in the rejection, but the degree of their participation differed. There was a low activation of T-lymphocytes and a high activation of B-lymphocytes in case of inflammatory processes, abscess, frunculosis, hematoma, etc., when stable doses of immunodepressants were used. The evidence of participation of T- and B-lymphocytes in the rejection opens new approaches to the diagnosis of different pathological conditions in the recipient's organism.

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