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Churg-Strauss 综合征相关性心力衰竭并左心室血栓形成。

Churg-Strauss syndrome-associated heart failure and left ventricular thrombosis.

机构信息

Second Department of Cardiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Rheumatology and Clinical Immunology Unit, Fourth Department of Internal Medicine, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

ESC Heart Fail. 2023 Jun;10(3):2107-2112. doi: 10.1002/ehf2.14244. Epub 2023 Mar 25.

DOI:10.1002/ehf2.14244
PMID:36965162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10192261/
Abstract

We present a case of a 47-year-old woman with a history of asthma and mononeuritis who presented with shortness of breath and fatigue. Heart failure was diagnosed and echocardiography revealed large floating thrombi attached to the left ventricular walls. Cardiac magnetic resonance imaging showed evidence of myocarditis and angiitis. Blood count revealed eosinophilia. She was diagnosed with eosinophilic granulomatosis with polyangiitis or Churg-Strauss syndrome (CSS) according to recently updated criteria. Medical management with specific aetiology (anticoagulation or immunosuppression) and heart failure treatment resulted in clinical improvement. We further discuss the diagnostic approach of CSS with cardiovascular complications and therapeutic management.

摘要

我们报告一例 47 岁女性患者，有哮喘和单神经炎病史，表现为呼吸急促和疲劳。诊断为心力衰竭，超声心动图显示左心室壁附着大的漂浮血栓。心脏磁共振成像显示心肌炎和血管炎的证据。血常规显示嗜酸性粒细胞增多。根据最近更新的标准，她被诊断为嗜酸性肉芽肿伴多血管炎或 Churg-Strauss 综合征（CSS）。采用特定病因（抗凝或免疫抑制）和心力衰竭治疗的药物治疗导致临床改善。我们进一步讨论 CSS 伴心血管并发症的诊断方法和治疗管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/9ec0a8b66d7c/EHF2-10-2107-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/09d93db658fc/EHF2-10-2107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/9b3bb033f348/EHF2-10-2107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/1288c7e8824e/EHF2-10-2107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/55b94337d4a8/EHF2-10-2107-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/5e7bedd86b82/EHF2-10-2107-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/9ec0a8b66d7c/EHF2-10-2107-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/09d93db658fc/EHF2-10-2107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/9b3bb033f348/EHF2-10-2107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/1288c7e8824e/EHF2-10-2107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/55b94337d4a8/EHF2-10-2107-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/5e7bedd86b82/EHF2-10-2107-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a44b/10192261/9ec0a8b66d7c/EHF2-10-2107-g006.jpg

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Systematic Review and Metaanalysis of Worldwide Incidence and Prevalence of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis.抗中性粒细胞胞浆抗体（ANCA）相关血管炎全球发病率和患病率的系统评价与Meta分析
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2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis.
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Clin Case Rep. 2025 Apr 17;13(4):e70427. doi: 10.1002/ccr3.70427. eCollection 2025 Apr.
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Acute heart failure due to fulminant eosinophilic myocarditis with mononeuritis: eosinophilic granulomatosis with polyangiitis requiring cardiac multimodality imaging and systemic evaluation: a case report.暴发性嗜酸性粒细胞性心肌炎合并单神经炎所致急性心力衰竭：嗜酸性粒细胞性肉芽肿性多血管炎需心脏多模态成像及全身评估：病例报告
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