头颈部鳞状细胞癌的寡转移情况：皮埃蒙特和瓦莱达奥斯塔肿瘤网络多学科团队的批判性综述
The oligometastatic setting in HNSCC: A critical review by the Rete Oncologica Piemonte e Valle d'Aosta multidisciplinary team.
作者信息
Denaro Nerina, Succo Giovanni, Ostellino Oliviero, Airoldi Mario, Merlano Marco Carlo, Badellino Serena, Solinas Cinzia, Garrone Ornella, Iorio Giuseppe Carlo
机构信息
Department of Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Oncology Department, Head & Neck Surgery, University of Turin, Turin, Italy.
出版信息
Crit Rev Oncol Hematol. 2023 May;185:103968. doi: 10.1016/j.critrevonc.2023.103968. Epub 2023 Mar 23.
INTRODUCTION
The oligometastatic disease is a low burden metastatic disease that might still benefit from curable treatment. Squamous cell carcinoma of the head and neck (HNSCC) is a complex group of malignancies, with high rates of loco-regional recurrences. Distant metastases are less frequent, and a single or few deposits are often observed (oligometastatic disease). The optimal management of oligometastatic HNSCC remains to be defined.
MATERIALS AND METHODS
Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used.
RESULTS
This paper contains a narrative report and a critical discussion of the available evidence on the management of oligometastatic HNSCC patients, with a focus on metastasis-directed therapy (MDT), particularly stereotactic ablative radiotherapy (SABR).
CONCLUSIONS
in line with literature data, the multidisciplinary evaluation emerged as the key element in the management of oligometastatic HNSCC patients.
引言
寡转移疾病是一种低负荷转移性疾病，可能仍可从可治愈性治疗中获益。头颈部鳞状细胞癌（HNSCC）是一组复杂的恶性肿瘤，局部区域复发率高。远处转移较少见，常观察到单个或少数转移灶（寡转移疾病）。寡转移HNSCC的最佳治疗方案仍有待确定。
材料与方法
关键参考文献来自PubMed查询。还采用了手工检索和ClinicalTrials.gov。
结果
本文包含一份叙述性报告以及对寡转移HNSCC患者治疗现有证据的批判性讨论，重点是转移灶定向治疗（MDT），尤其是立体定向消融放疗（SABR）。
结论
与文献数据一致，多学科评估成为寡转移HNSCC患者治疗的关键要素。
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