Rodríguez Escobedo Raúl, Delgado Álvarez Elías, Menéndez Torre Edelmiro Luis
Hospitales Universitarios San Roque, Las Palmas de Gran Canaria, Spain; Grupo de Investigación en Endocrinología, Nutrición, Diabetes y Obesidad, Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain.
Grupo de Investigación en Endocrinología, Nutrición, Diabetes y Obesidad, Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain; Hospital Universitario Central de Asturias, Oviedo, Spain; Departamento de Medicina. Universidad de Oviedo, Oviedo, Spain; Centro de Investigación Biomédica en Enfermedades Raras (CIBERER).
Endocrinol Diabetes Nutr (Engl Ed). 2023 Mar;70(3):189-195. doi: 10.1016/j.endien.2023.03.008. Epub 2023 Mar 23.
Type 1 diabetes mellitus (DM1) is a chronic disease with important socio-health repercussions that requires epidemiological information for proper health management. The aim of this study was to determine the incidence of DM1 in Asturias between 2011-2020.
Descriptive study which included diagnoses of DM1 in Asturias between 2011-2020 captured as a primary source by reviewing the register of pancreatic autoimmunity analysis. Incidence rates were estimated, expressed per 100,000 population-years of risk by age group, sex, and health area.
A total of 815 patients were diagnosed, 53.13% men. The mean age was 34.32±22.07 years; 9.85±4.46 in children under 19 years of age (10.48±4.45 in males and 9.00±4.36 in females). Of the diagnoses, 55.34% occurred at an age over 30 years. The incidence was 7.82 (7.29-8.37); 19.65 (17.17-22.39) in under 15s and 12.84 (11.73-14.03) in under 40s. The maximum incidence peak was between 10-14 years, both in males 31.16 (23.89-39.95) and in females 21.72 (15.59-29.47). There was no significant increase in incidence over the years studied.
Asturias has a high incidence of DM1. In our study no earlier age at diagnosis was observed or an increase in incidence. Compared to previous studies, the increase in incidence is most likely due to an improvement in data capture, not to a real increase in incidence. A high percentage of diagnoses occur in adulthood.
1型糖尿病(DM1)是一种具有重要社会健康影响的慢性疾病,需要流行病学信息以进行适当的健康管理。本研究的目的是确定2011年至2020年间阿斯图里亚斯地区DM1的发病率。
描述性研究,纳入2011年至2020年间阿斯图里亚斯地区DM1的诊断病例,通过查阅胰腺自身免疫分析登记册作为主要来源获取数据。按年龄组、性别和健康区域估计发病率,以每100,000人口-年风险表示。
共诊断出815例患者,男性占53.13%。平均年龄为34.32±22.07岁;19岁以下儿童为9.85±4.46岁(男性为10.48±4.45岁,女性为9.00±4.36岁)。在诊断病例中,55.34%发生在30岁以上。发病率为7.82(7.29 - 8.37);15岁以下为19.65(17.17 - 22.39),40岁以下为12.84(11.73 - 14.03)。发病率最高峰值出现在10 - 14岁,男性为31.16(23.89 - 39.95),女性为21.72(15.59 - 29.47)。在所研究的年份中发病率没有显著增加。
阿斯图里亚斯地区DM1发病率较高。在我们的研究中未观察到诊断年龄提前或发病率增加的情况。与先前研究相比,发病率增加最有可能是由于数据收集的改善,而非发病率的实际增加。高比例的诊断发生在成年期。