Department for Radiology and Neuroradiology, Universityhospital Schleswig Holstein (UKSH), Kiel University, Campus Kiel, Arnold-Heller-Street 3, Building D, 24105, Kiel, Germany.
Sci Rep. 2023 Mar 25;13(1):4904. doi: 10.1038/s41598-023-31877-1.
The novel Contour device is an intrasaccular flow disruption device designed for treatment of intracranial wide-neck bifurcation aneurysms. Outside its original purpose, Contour implantation can be used to treat aneurysms with a higher dome-to-neck ratio which would be suitable for conventional unassisted coil embolization. We compared both techniques in a retrospective single-center analysis. A total of 42 aneurysms from 42 patients with a dome-to-neck ratio of 1.6 or higher were included in this study. Data on technical success, implantation times, radiation dosages, procedural complications, reinterventions and recurrences were gathered and compared. Technical success was achieved in all cases with both techniques. Aneurysm embolization was achieved significantly faster in the Contour group compared to coiling (Overall p = 0.0002; r = 0.580; acute setting: p = 0.005, r = 0.531; elective setting: p = 0.002, r = 0.607). Significantly less radiation dosage was applied in the Contour group (Overall p = 0.002; r = 0.478; acute group p = 0.006; r = 0.552; elective group p = 0.045; r = 0.397). The number of complications was higher in the coiling group compared to the Contour group (Coiling 7/21 (33,3%); Contour 3/21 (14.3%). There was a higher rate of reinterventions in the coiling group (7.6% vs 21.4%). Outside its original intention, the Contour device seems to be a safe and fast alternative to coil embolization for the treatment of narrow-neck-aneurysms.
新型 Contour 装置是一种腔内血流破坏装置，设计用于治疗颅内宽颈分叉动脉瘤。在其原始用途之外，Contour 植入术可用于治疗瘤颈比更高的动脉瘤，这些动脉瘤适合传统的无辅助线圈栓塞。我们在一项回顾性单中心分析中比较了这两种技术。本研究共纳入了 42 名患者的 42 个动脉瘤，这些动脉瘤的瘤颈比为 1.6 或更高。收集并比较了技术成功率、植入时间、辐射剂量、程序并发症、再干预和复发的数据。两种技术均在所有病例中达到了技术成功。与线圈栓塞相比，Contour 组的动脉瘤栓塞速度明显更快（总体 p=0.0002；r=0.580；急性组 p=0.005，r=0.531；择期组 p=0.002，r=0.607）。Contour 组的辐射剂量明显较少（总体 p=0.002；r=0.478；急性组 p=0.006；r=0.552；择期组 p=0.045；r=0.397）。与 Contour 组相比，线圈栓塞组的并发症发生率更高（线圈栓塞 7/21（33.3%）；Contour 组 3/21（14.3%）。线圈栓塞组的再干预率更高（7.6%比 21.4%）。在其原始意图之外，Contour 装置似乎是一种安全且快速的替代线圈栓塞治疗窄颈动脉瘤的方法。
