IgG4 和 IgE 抗粪类圆线虫抗体作为高流行地区糖尿病患者特征的附加参数。
IgG4 and IgE anti-Strongyloides stercoralis as additional parameters in characterizing patients with diabetes from a hyperendemic area.
机构信息
Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais State, Brazil.
Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais State, Brazil.
出版信息
Diagn Microbiol Infect Dis. 2023 May;106(1):115927. doi: 10.1016/j.diagmicrobio.2023.115927. Epub 2023 Mar 1.
We report the detection of IgG, IgG1, IgG4 and IgE anti-Strongyloides stercoralis as complementary tool for screening in patients with diabetes in hyperendemic areas for strongyloidiasis. A panel of 119 serum samples were analyzed: 76 from patients with DM2 and 43 patients with other endocrine diseases and a positive correlation for total IgG levels with IgG4 (rs = 0.559; P = 0.024; n = 16) and IgG and IgE (rs = 0.585; P < 0.0001; n = 76) was found in the diabetes group.
我们报告了 IgG、IgG1、IgG4 和 IgE 抗旋毛虫的检测，作为在强旋毛虫病高度流行地区筛查糖尿病患者的补充工具。分析了一组 119 份血清样本：76 份来自 2 型糖尿病患者，43 份来自其他内分泌疾病患者，发现糖尿病组总 IgG 水平与 IgG4（rs=0.559；P=0.024；n=16）和 IgG 与 IgE（rs=0.585；P<0.0001；n=76）呈正相关。
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