Smell & Taste Clinic, Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Faculty of Psychology, Southwest University, Chongqing, China.
Neuroscience. 2023 Jun 1;520:144-155. doi: 10.1016/j.neuroscience.2023.03.011. Epub 2023 Mar 24.
Taste and oral somatosensation are intimately related to each other from peripheral receptors to the central nervous system. Oral astringent sensation is thought to contain both gustatory and somatosensory components. In the present study, we compared the cerebral response to an astringent stimulus (tannin), with the response to one typical taste stimulus (sweet - sucrose) and one typical somatosensory stimulus (pungent - capsaicin) using functional magnetic resonance imaging (fMRI) of 24 healthy subjects. Three distributed brain sub-regions responded significantly different to the three types of oral stimulations: lobule IX of the cerebellar hemisphere, right dorsolateral superior frontal gyrus, and left middle temporal gyrus. This suggests that these regions play a major role in the discrimination of astringency, taste, and pungency.
味觉和口腔体感密切相关，从外周受体到中枢神经系统都是如此。口腔涩感被认为既包含味觉成分，也包含体感成分。在本研究中，我们使用 24 名健康受试者的功能磁共振成像（fMRI），比较了涩味刺激（单宁）、典型味觉刺激（甜-蔗糖）和典型体感刺激（辣-辣椒素）引起的大脑反应。三个分布式脑区对三种口腔刺激的反应明显不同：小脑脑桥叶 IX 区、右侧额上外侧回和左侧颞中回。这表明这些区域在涩味、味觉和辣味的辨别中起着重要作用。
