Johnson A L, Taylor D W, Sackett D L, Dunnett C W, Shimizu A G
Can Med Assoc J. 1978 Nov 4;119(9):1034-9.
The efficacy of self-recording of blood pressure in the management of hypertension was assessed in a randomized clinical trial involving 140 persons who had been receiving antihypertensive therapy for a year or more, but whose diastolic blood pressure had remained at 95 mm Hg or higher. To control for the increased attention implicit in self-recording, which might affect blood pressure, the patients were assigned at random to one of the four groups: self-recording and monthly home visits, self-recording only, monthly home visits only, and neither self-recording nor monthly home visits. This design also permitted assessment of the effect of home visits. During the 6-month experiment no significant differences were apparent between the groups in either compliance or diastolic blood pressure. However, both self-recording and monthly home visits produced a reduction in blood pressure among patients who admitted to difficulty remembering to take their pills; a reduction was not seen among patients who said they had no such difficulty. This confirmed an earlier observation suggesting that this easily identified group of patients may be the most responsive to intervention programs.
在一项随机临床试验中，对140名接受抗高血压治疗一年或更长时间但舒张压仍保持在95毫米汞柱或更高的患者进行了血压自我记录在高血压管理中的疗效评估。为了控制自我记录中隐含的更多关注（这可能会影响血压），患者被随机分配到四组中的一组：自我记录并每月进行家访、仅自我记录、仅每月进行家访以及既不自我记录也不进行每月家访。这种设计还允许评估家访的效果。在为期6个月的实验中，各组在依从性或舒张压方面均未出现显著差异。然而，自我记录和每月家访都使那些承认难以记住服药的患者血压有所降低；而那些表示没有此类困难的患者血压并未降低。这证实了早期的一项观察结果，即这一易于识别的患者群体可能对干预方案反应最为敏感。
