Taren D L, Nesheim M C, Crompton D W, Holland C V, Barbeau I, Rivera G, Sanjur D, Tiffany J, Tucker K
College of Public Health, University of South Florida.
Parasitology. 1987 Dec;95 ( Pt 3):603-13. doi: 10.1017/s0031182000058029.
Relationships between ascariasis and lactose digestion and between ascariasis and food transit time from mouth to caecum were investigated in young children from Chiriqui Province, Republic of Panama. The breath hydrogen method was used in both studies. Ascaris-infected children showed a significantly poorer degree of lactose digestion following a test oral load than uninfected children. Recovery of the capacity of the children to digest lactose was still not fully complete for at least 3 weeks following anthelmintic treatment. On average, the mouth-to-caecum transit time was similar in infected and uninfected children, but among the Ascaris-infected children the transit time tended to be shorter in relation to the intensity of infection. Evidence from a cross-sectional survey indicated that ascariasis was significantly associated with reduced plasma vitamin A and carotenoid concentrations. This relationship remained after controlling for a range of socio-economic variables. Ascaris-infected children were frequently found to have lower haematocrits and blood haemoglobin concentrations than uninfected children, but these relationships could not be attributed to ascariasis alone.
在巴拿马共和国奇里基省的幼儿中，研究了蛔虫病与乳糖消化之间的关系，以及蛔虫病与食物从口腔到盲肠的传输时间之间的关系。两项研究均采用呼气氢法。与未感染的儿童相比，感染蛔虫的儿童在口服负荷试验后乳糖消化程度明显较差。驱虫治疗后至少3周，儿童消化乳糖的能力仍未完全恢复。平均而言，感染和未感染儿童的口腔到盲肠传输时间相似，但在感染蛔虫的儿童中，传输时间往往与感染强度呈负相关。横断面调查的证据表明，蛔虫病与血浆维生素A和类胡萝卜素浓度降低显著相关。在控制一系列社会经济变量后，这种关系依然存在。经常发现感染蛔虫的儿童的血细胞比容和血红蛋白浓度低于未感染的儿童，但这些关系不能仅归因于蛔虫病。
