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危地马拉农村学龄前儿童的血液视黄醇和β-胡萝卜素水平

Blood retinol and beta-carotene levels in rural Guatemalan preschool children.

作者信息

Romero-Abal M E, Mendoza I, Bulux J, Solomons N W

机构信息

CeSSIAM, Hospital Dr Rodolfo Robles V, Guatemala City, Guatemala.

出版信息

Eur J Epidemiol. 1995 Apr;11(2):133-9. doi: 10.1007/BF01719477.

DOI:10.1007/BF01719477
PMID:7672065
Abstract

Plasma retinol and beta-carotene levels were measured in 502 preschool Guatemalan children from five rural hamlets. Their ages ranged from 6 to 78 months (mean: 42.9 +/- 19.2 months); 45% males and 55% females. The mean retinol value in the whole group was 0.9 +/- 0.4 mumol/l (range: 0.1 to 8.4 mumol/l). There was no significant difference between sexes in retinol mean values nor in the incidence of retinol values less than 0.7 mumol/l (22% in males, 18% in females). When grouped by age and community, significant low retinol mean values were found in two hamlets in the youngest age group (12 to 23 months) as compared to the other age-groups (p < 0.05). In the other two hamlets, there were no significant differences among retinol means by age-group. The highest prevalence of deficient retinol values by age-group was in the 12 to 23 months group (40%), and decreased as age increased. The mean value for beta-carotene in the whole group was 0.13 +/- 0.18 mumol/l (range: 0.01 to 2.23 mumol/l). There were no significant differences in beta-carotene means between sexes in the whole group. Stratifying the beta-carotene data by age-groups and community, values were significantly higher in the 48-59 months and 72-83 months groups, as compared with the other age groups in two of the communities (p < 0.05). Significant differences across communities for beta-carotene were found only in the 12 to 23 months group.

摘要

对来自危地马拉五个乡村小村庄的502名学龄前儿童测量了血浆视黄醇和β-胡萝卜素水平。他们的年龄在6至78个月之间(平均:42.9±19.2个月);男性占45%,女性占55%。整个组的视黄醇平均值为0.9±0.4μmol/l(范围:0.1至8.4μmol/l)。视黄醇平均值在性别之间以及视黄醇值低于0.7μmol/l的发生率(男性为22%,女性为18%)方面均无显著差异。按年龄和社区分组时,与其他年龄组相比,在最年幼年龄组(12至23个月)的两个小村庄中发现视黄醇平均水平显著较低(p<0.05)。在其他两个小村庄中,各年龄组的视黄醇平均值之间无显著差异。按年龄组划分,视黄醇值缺乏的最高患病率出现在12至23个月组(40%),且随年龄增长而降低。整个组的β-胡萝卜素平均值为0.13±0.18μmol/l(范围:0.01至2.23μmol/l)。整个组中β-胡萝卜素平均值在性别之间无显著差异。按年龄组和社区对β-胡萝卜素数据进行分层时,在两个社区中,48 - 59个月组和72 - 83个月组的值与其他年龄组相比显著更高(p<0.05)。仅在12至23个月组中发现不同社区之间β-胡萝卜素存在显著差异。

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本文引用的文献

1
The effect of vitamin A fortification of sugar on the serum vitamin A levels of preschool Guatemalan children: a longitudinal evaluation.糖中强化维生素A对危地马拉学龄前儿童血清维生素A水平的影响:一项纵向评估
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Low vitamine A and zinc concentrations in Mexican-American migrant children with growth retardation.生长发育迟缓的墨西哥裔美国移民儿童体内维生素A和锌浓度偏低。
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The effect of vitamin A fortification of sugar on iron metabolism in preschool children in Guatemala.
危地马拉学龄前儿童中糖强化维生素A对铁代谢的影响。
Am J Clin Nutr. 1982 Jul;36(1):87-93. doi: 10.1093/ajcn/36.1.87.
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Clinical chemical methods for the routine assessment of the vitamin status in human populations. Part II: The water-soluble vitamins B1, B2 and B6.用于人群维生素状况常规评估的临床化学方法。第二部分:水溶性维生素B1、B2和B6。
Int J Vitam Nutr Res. 1983;53(4):359-70.
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Serum levels of vitamin A and carotenoids as reflectors of nutritional status.血清维生素A和类胡萝卜素水平作为营养状况的反映指标。
J Natl Cancer Inst. 1984 Dec;73(6):1439-44.
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Vitamin A status of young children in Southern Brazil.巴西南部幼儿的维生素A状况。
Am J Clin Nutr. 1986 May;43(5):852-8. doi: 10.1093/ajcn/43.5.852.
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Contributions of ascariasis to poor nutritional status in children from Chiriqui Province, Republic of Panama.巴拿马共和国奇里基省蛔虫病对儿童营养状况不佳的影响。
Parasitology. 1987 Dec;95 ( Pt 3):603-13. doi: 10.1017/s0031182000058029.
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Effect of an infection on vitamin A status of children as measured by the relative dose response (RDR).通过相对剂量反应(RDR)测定感染对儿童维生素A状况的影响。
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Effect of deworming and vitamin A administration on serum vitamin A levels in preschool children.
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