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人类免疫缺陷病毒感染合并甲状腺乳头状癌的甲状腺功能亢进症:病例报告及文献综述

Hyperthyroidism with papillary thyroid carcinoma in HIV: Case report and literature review.

作者信息

Guan Yang Yang

机构信息

Department of Thyroid and Mammary Surgery, Affiliated Hospital of Panzhihua University, China.

出版信息

Heliyon. 2023 Mar 9;9(3):e14377. doi: 10.1016/j.heliyon.2023.e14377. eCollection 2023 Mar.

DOI:10.1016/j.heliyon.2023.e14377
PMID:36967896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10034455/
Abstract

The immune function of HIV infected patients is severely damaged, which can cause a series of autoimmune related diseases including hyperthyroidism. Hyperthyroidism includes both primary and secondary hyperthyroidism. Graves' disease is the most common primary hyperthyroidism, and Graves' disease may occur in HIV patients during immune reconstitution after antiretroviral therapy A 47-year-old woman with a history of HIV presented with symptoms related to hyperthyroidism. After antithyroid drug therapy failed, the patient and her families opted for surgical treatment. Postoperative examination revealed papillary thyroid carcinoma.

摘要

HIV感染患者的免疫功能严重受损,这可导致一系列自身免疫相关疾病,包括甲状腺功能亢进症。甲状腺功能亢进症包括原发性和继发性甲状腺功能亢进症。格雷夫斯病是最常见的原发性甲状腺功能亢进症,格雷夫斯病可能在抗逆转录病毒治疗后的HIV患者免疫重建期间出现。一名有HIV病史的47岁女性出现了与甲状腺功能亢进症相关的症状。抗甲状腺药物治疗失败后,患者及其家属选择了手术治疗。术后检查发现甲状腺乳头状癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adcd/10034455/4c5d58ec5d57/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adcd/10034455/015ff8ae6df7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adcd/10034455/4c5d58ec5d57/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adcd/10034455/015ff8ae6df7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adcd/10034455/4c5d58ec5d57/gr2.jpg

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本文引用的文献

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Immune reconstitution inflammatory syndrome-associated Graves disease in HIV-infected patients: clinical characteristics and response to radioactive iodine therapy.HIV 感染者中与免疫重建炎症综合征相关的 Graves 病:临床特征及放射性碘治疗的反应。
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Hyperthyroidism.甲状腺功能亢进症。
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Autoimmune diseases in HIV-infected patients: 52 cases and literature review.HIV 感染者的自身免疫性疾病:52 例病例及文献复习。
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Evaluation of thyroid function and autoimmunity in HIV-infected women.对感染HIV的女性甲状腺功能和自身免疫性的评估。
Arq Bras Endocrinol Metabol. 2013 Aug;57(6):450-6. doi: 10.1590/s0004-27302013000600007.
9
Graves' disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4(+) T-cell recovery.HIV 阳性患者中的格雷夫斯病是免疫重建疾病,与幼稚和初始胸腺迁出 CD4(+)T 细胞的恢复有关。
AIDS. 2014 Jan 2;28(1):31-9. doi: 10.1097/QAD.0000000000000006.
10
Hashimoto's thyroiditis presenting as acute painful thyroiditis and as a manifestation of an immune reconstitution inflammatory syndrome in a human immunodeficiency virus-seropositive patient.桥本甲状腺炎表现为急性痛性甲状腺炎和人类免疫缺陷病毒血清阳性患者免疫重建炎症综合征的一种表现。
Thyroid. 2012 Aug;22(8):853-5. doi: 10.1089/thy.2012.0055. Epub 2012 Jul 11.