Clarke Lionel
BionerG Chester UK.
Eng Biol. 2020 Dec 2;4(3):33-36. doi: 10.1049/enb.2020.0021. eCollection 2020 Dec.
'Engineering biology' is being increasingly adopted as a term by organisations that seek to deliver benefits from 'synthetic biology'. However, are 'engineering biology' and 'synthetic biology' different words with the same meaning or do they signal important differences? By observing how these two terms are currently being described and applied in practice, it is possible to differentiate the two whilst also acknowledging significant overlaps and complementarity. Increasing adoption of the term 'engineering biology' reflects the maturing of synthetic biology since the early years of this century from a research concept to a technological platform that is facilitating the delivery of commercial products and services. The term 'synthetic biology' retains a strong association with its original goal to help make biology engineerable, a challenge that will inevitably continue to stimulate research for decades to come as ever more complex and demanding systems are tackled. In comparison, the term 'engineering biology' relates more commonly to the utilisation of the synthetic biology platform alongside other related technologies to deliver effective solutions in response to increasing market challenges and expectations.
“工程生物学”正越来越多地被那些试图从“合成生物学”中获取益处的组织用作一个术语。然而,“工程生物学”和“合成生物学”是含义相同的不同词汇,还是意味着重要的差异呢?通过观察这两个术语目前在实践中的描述和应用方式,在承认显著重叠和互补性的同时,也能够区分两者。“工程生物学”这一术语使用的增加反映了合成生物学自本世纪初以来从一个研究概念发展成为一个技术平台的成熟过程,该技术平台正在推动商业产品和服务的交付。“合成生物学”一词与其最初的目标——使生物学具有可工程性,仍有着紧密联系,随着越来越复杂和要求更高的系统被攻克,这一挑战在未来几十年将不可避免地继续刺激研究。相比之下,“工程生物学”一词更普遍地涉及合成生物学平台与其他相关技术的利用,以应对不断增加的市场挑战和期望,从而提供有效的解决方案。