用于筛查抗高血压药物依从性的头发分析的测量工具和效用。
Measurement Tools and Utility of Hair Analysis for Screening Adherence to Antihypertensive Medication.
机构信息
Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa.
Medical School, University of Western Australia, Harry Perkins Institute of Medical Sciences, Fiona Stanley Hospital, Verdun Street, Nedlands WA, 6009, Australia.
出版信息
Glob Heart. 2023 Mar 22;18(1):17. doi: 10.5334/gh.1191. eCollection 2023.
Poor adherence to the prescribed antihypertensive therapy is an understated public health problem and is one of the main causes of the high prevalence of uncontrolled hypertension in sub-Saharan Africa. Medication adherence is vital for the effectiveness of antihypertensive treatment and is key to ameliorating the clinical outcomes in hypertensive patients. However, it has often been ignored because the current methods used to assess medication adherence are not reliable, limiting their utilization in clinical practice. Therefore, the identification of the most accurate and clinically feasible method for measuring medication adherence is critical for tailoring effective strategies to improve medication adherence and consequently achieve blood pressure goals. This review not only explores various available methods for estimating medication adherence but also proposes therapeutic drug monitoring in hair for the measurement of medication adherence to the antihypertensive medication period.
抗高血压治疗的依从性差是一个被低估的公共卫生问题，也是撒哈拉以南非洲地区高血压未得到控制的高患病率的主要原因之一。药物依从性对抗高血压治疗的有效性至关重要，是改善高血压患者临床结局的关键。然而，由于目前用于评估药物依从性的方法不可靠，因此常常被忽视，这限制了它们在临床实践中的应用。因此，确定最准确和临床可行的测量药物依从性的方法对于制定有效的策略以提高药物依从性并最终实现血压目标至关重要。本综述不仅探讨了评估药物依从性的各种现有方法，还提出了在头发中进行治疗药物监测以测量抗高血压药物期间的药物依从性。
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