Suppr超能文献

侵袭性葡萄胎酷似异常子宫出血:一例报告

Invasive Mole Mimicking Abnormal Uterine Bleeding: A Case Report.

作者信息

Sankhe Darshan D, Somalwar Savita, Jiandani Farah, Jain Sheela, Shetty Anushree

机构信息

Department of Obstetrics and Gynaecology, Narendra Kumar Prasadrao (NKP) Salve Institute of Medical Sciences and Research Centre, Nagpur, IND.

出版信息

Cureus. 2023 Feb 19;15(2):e35195. doi: 10.7759/cureus.35195. eCollection 2023 Feb.

Abstract

Invasive mole (IM) is a very uncommon subtype of gestational trophoblastic disease (GTD), which is the invasion of molar tissue into the uterine or myometrial vasculature. However, this report presents a rare case of a 41-year-old female multiparous P7 with five full-term normal vaginal deliveries and two preterm normal vaginal deliveries. As the patient was not using contraception, her urine pregnancy test (UPT) was done, which demonstrated positive results. A speculum examination revealed a healthy cervix with just mild bleeding, whereas a vaginal examination revealed a firm cervix and an anteverted and mobile eight-week-old uterus along with a free fornix. Pelvic ultrasound and magnetic resonance imaging (MRI) demonstrated the diagnosis of GTD, for which consultation from an oncology physician was taken and the treatment proceeded with a total abdominal hysterectomy. Histological examination of the uterus showed a circumscribed nodule showing a large area of hemorrhage with few chorionic villi lined with trophoblastic cells and occasional villi invading the myometrium and endometrial cavity suggesting hydatidiform mole showing early invasion that confirmed the diagnosis of IM. In conclusion, reproductive-age women who experience abnormal uterine bleeding (AUB) should suspect pregnancy with several possible complications, for which a pregnancy test should be done to rule out complications.

摘要

侵袭性葡萄胎(IM)是妊娠滋养细胞疾病(GTD)中一种非常罕见的亚型,是指葡萄胎组织侵入子宫或肌层血管。然而,本报告介绍了一例罕见病例,患者为41岁经产妇,孕7产,有5次足月正常阴道分娩和2次早产正常阴道分娩。由于患者未采取避孕措施,进行了尿妊娠试验(UPT),结果呈阳性。窥器检查显示宫颈健康,仅有轻度出血,而阴道检查显示宫颈坚硬,子宫前倾且可活动,妊娠8周大小,穹窿部无异常。盆腔超声和磁共振成像(MRI)确诊为GTD,为此咨询了肿瘤内科医生,并进行了全腹子宫切除术。子宫组织学检查显示有一个边界清楚的结节,有大面积出血,有少量绒毛膜绒毛,衬有滋养层细胞,偶尔有绒毛侵入肌层和子宫内膜腔,提示葡萄胎早期侵袭,确诊为侵袭性葡萄胎。总之,出现异常子宫出血(AUB)的育龄妇女应怀疑妊娠并伴有多种可能的并发症,为此应进行妊娠试验以排除并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9803/10032175/7b2ed860c58e/cureus-0015-00000035195-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验