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病例报告:急慢性疾病患儿的横纹肌溶解症——儿科急诊医学中的一种具有挑战性的病症

Case report: Rhabdomyolysis in children in acute and chronic disease-a challenging condition in pediatric emergency medicine.

作者信息

Mand N, Donath C, Leonhardt A, Weber S, Kömhoff M

机构信息

Pediatric Intensive Care, Department of Pediatrics, Philipps-University Marburg, Marburg, Germany.

Pediatric Nephrology, Department of Pediatrics, Philipps-University Marburg, Marburg, Germany.

出版信息

Front Pediatr. 2023 Mar 9;11:1070465. doi: 10.3389/fped.2023.1070465. eCollection 2023.

Abstract

Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), acute kidney injury (AKI), and multi-organ disease. Most common causes of rhabdomyolysis are viral myositis and trauma, hereditary metabolic myopathies must be considered when facing rhabdomyolysis in early childhood. We report two cases of severe rhabdomyolysis with CF in our PED, thereby summarizing first-line management of rhabdomyolysis.

摘要

横纹肌溶解症在儿科急诊科是一种具有挑战性的病症

它涵盖从肌酸激酶(CK)水平孤立升高的无症状疾病到与CK极度升高、电解质失衡、循环衰竭(CF)、急性肾损伤(AKI)和多器官疾病相关的危及生命的病症。横纹肌溶解症最常见的病因是病毒性肌炎和创伤,在幼儿期面对横纹肌溶解症时必须考虑遗传性代谢性肌病。我们报告了我们儿科急诊科两例伴有循环衰竭的严重横纹肌溶解症病例,从而总结横纹肌溶解症的一线治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8c4/10034202/ee7c70a05df7/fped-11-1070465-g001.jpg

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