Szugye Heidi S
Cleveland Clinic Children's, Cleveland Clinic Lerner College of Medicine, Cleveland, OH.
Pediatr Rev. 2020 Jun;41(6):265-275. doi: 10.1542/pir.2018-0300.
Pediatric rhabdomyolysis is a common diagnosis that pediatricians need to be able to recognize because prompt treatment can prevent potential complications, such as acute kidney injury. The triggers for rhabdomyolysis are extensive, with viruses being the most common cause in pediatric patients. The pathophysiology behind rhabdomyolysis is complex and still being researched, but having a firm understanding of the cascade that results when muscle injury occurs is essential for proper management. Guidelines for managing pediatric rhabdomyolysis currently do not exist, but this article aims to review the available literature and give clinicians a general approach to aid in history taking, physical examination, diagnosis, acute management, follow-up, and prevention.
小儿横纹肌溶解症是一种常见诊断，儿科医生需要能够识别，因为及时治疗可预防潜在并发症，如急性肾损伤。横纹肌溶解症的诱因广泛，病毒是儿科患者中最常见的病因。横纹肌溶解症背后的病理生理学很复杂，仍在研究中，但深入了解肌肉损伤发生时的连锁反应对于正确处理至关重要。目前尚无小儿横纹肌溶解症的管理指南，但本文旨在综述现有文献，并为临床医生提供一种通用方法，以协助进行病史采集、体格检查、诊断、急性处理、随访及预防。
