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新冠后综合征中的睡眠障碍:是精神问题还是神经问题?

Sleep Disorders in Post-COVID Syndrome: A Psychiatric or Neurological Problem?

作者信息

Kotova O V, Medvedev V E, Poluektov M G, Belyaev A A, Akarachkova E S

机构信息

Peoples' Friendship University of Russia, Moscow, Russia.

International Association "Stress Under Control,", Moscow, Russia.

出版信息

Neurosci Behav Physiol. 2023;53(1):16-20. doi: 10.1007/s11055-023-01385-w. Epub 2023 Mar 11.

Abstract

The coronavirus pandemic that began in 2019 continues. COVID-19 adversely affects human health not only in the acute, but also in the long-term period of the disease: in a large percentage of cases, health is not fully restored after long periods, requires medical intervention, and is often difficult to correct. Researchers noted during the first wave of the pandemic in 2020 that about 10-20% of patients did not fully recover by three weeks from disease onset and the possible duration of the recovery period remains insufficiently clear, as do the reasons for differences in course during this period. Prolonged recovery after viral infection is not a feature exclusive to COVID-19, which does not facilitate the management of patients with post-COVID syndrome (PCS). The mental health impact of COVID-19 is significant, with at least 30% of recovered patients likely to have symptoms of anxiety and/or depression after the acute phase has passed. Since the onset of COVID-19, there has been an increase in sleep disorders by 42%, with every third COVID-19 survivor reporting sleep complaints. In PCS, this condition is referred to as coronasomnia. The success of therapy for this condition depends on identifying and correcting patients' mental disorders, as anxiety and depression are often accompanied by sleep disorders this results in a bidirectional interaction between mental disorders and sleep quality. This article presents data on the anti-anxiety drugs Noofen and Adaptol, which help to correct the manifestations of PCS with sleep disorders.

摘要

始于2019年的新冠疫情仍在持续。新冠病毒不仅在急性期,而且在疾病的长期阶段都会对人类健康产生不利影响:在很大比例的病例中,长期后健康状况无法完全恢复,需要医疗干预,且往往难以纠正。研究人员在2020年疫情第一波期间指出,约10%-20%的患者在发病三周后未能完全康复,恢复期的可能时长仍不够明确,在此期间病程差异的原因也不明确。病毒感染后的长期恢复并非新冠病毒独有的特征,这给新冠后综合征(PCS)患者的管理带来了困难。新冠病毒对心理健康的影响很大,至少30%的康复患者在急性期过后可能出现焦虑和/或抑郁症状。自新冠疫情爆发以来,睡眠障碍增加了42%,每三名新冠病毒幸存者中就有一人报告有睡眠问题。在PCS中,这种情况被称为新冠失眠症。这种疾病的治疗成功取决于识别和纠正患者的精神障碍,因为焦虑和抑郁常常伴有睡眠障碍,这导致了精神障碍与睡眠质量之间的双向相互作用。本文介绍了抗焦虑药物诺芬和阿得尔托的数据,它们有助于纠正伴有睡眠障碍的PCS的症状。

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