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手指高流量动静脉畸形采用动脉止血带和微球囊闭塞技术经静脉注射油酸乙醇胺硬化治疗:一例报告

High-flow arteriovenous malformation in the finger with transvenous ethanolamine oleate sclerotherapy using an arterial tourniquet and microballoon occlusion: A case report.

作者信息

Tannai Hiromitsu, Oguro Sota, Nagao Munetomo, Ota Hideki, Takase Kei

机构信息

Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, 2...1 Seiryo...machi, Aoba...ku, Sendai, Miyagi, 980-8575, Japan.

Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

出版信息

Radiol Case Rep. 2023 Mar 20;18(5):1973-1977. doi: 10.1016/j.radcr.2023.02.048. eCollection 2023 May.

Abstract

Endovascular therapy is an important method of treating high-flow arteriovenous malformations (AVMs). The nidus of AVMs can be treated by transarterial or percutaneous approaches with the use of ethanol as a strong embolic agent; however, treatment outcomes are not always satisfactory and complications including skin necrosis often occur, particularly following the treatment of superficial lesions. Herein, we describe successful transvenous sclerotherapy of high-flow AVMs in the finger of a 47-year-old female patient that were causing erythema and spontaneous pain using ethanolamine oleate (EO) as a safe sclerosant. Dynamic contrast-enhanced computed tomography and angiography revealed a high-flow type Ⅲb AVM according to Yakes classification. Using the transvenous approach, 5% EO with idoxanol was injected into the nidus of the AVM 3 times over 2 sessions. An arterial tourniquet was used to achieve stasis of blood flow at the nidus and microballoon occlusion of the outflow vein was used to ensure the sclerosant effectively reached the nidus. Near-total occlusion of the nidus was achieved leading to improved symptoms. Mild edema lasting 2 weeks occurred as a minor reaction after each session. Finger amputation may have been avoided by using this treatment. Transvenous EO sclerotherapy using an arterial tourniquet and balloon occlusion may have utility in treating AVMs in the extremities.

摘要

血管内治疗是治疗高流量动静脉畸形(AVM)的重要方法。AVM的病灶可通过经动脉或经皮途径,使用乙醇作为强力栓塞剂进行治疗;然而,治疗效果并不总是令人满意,并且包括皮肤坏死在内的并发症经常发生,尤其是在治疗浅表病灶之后。在此,我们描述了一例47岁女性患者手指高流量AVM的成功经静脉硬化治疗,该AVM导致红斑和自发疼痛,使用油酸乙醇胺(EO)作为安全硬化剂。动态对比增强计算机断层扫描和血管造影显示,根据Yakes分类为高流量Ⅲb型AVM。采用经静脉途径,在2个疗程中3次将5% EO与碘克沙醇注入AVM病灶。使用动脉止血带使病灶处血流淤滞,并使用微球囊阻塞流出静脉,以确保硬化剂有效到达病灶。病灶几乎完全闭塞,症状得到改善。每次疗程后出现持续2周的轻度水肿,为轻微反应。采用这种治疗方法可能避免了手指截肢。使用动脉止血带和球囊阻塞的经静脉EO硬化治疗可能对治疗四肢AVM有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10036881/b4945745de0a/gr1.jpg

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