Lu Xianying, Wu Chenxi, Bai Dingxi, You Qian, Cai Mingjin, Wang Wei, Hou Chaoming, Gao Jing
School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Front Psychiatry. 2023 Mar 8;14:1136013. doi: 10.3389/fpsyt.2023.1136013. eCollection 2023.
To quantitatively analyze the association between social support (SS) and fear of cancer recurrence (FCR) by reviewing current evidence from observational studies.
A comprehensive literature search was performed in nine databases from inception to May 2022. Observational studies that used both SS and FCR as study variables were included. Regression coefficient (β') and correlation coefficient () were calculated with R software. Subgroup analysis was utilized to investigate the degree of the relationship between SS and FCR as well as the impact of various forms of SS on FCR in cancer patients.
Thirty-seven studies involving 8,190 participants were identified. SS significantly reduced FCR risk [pooled β' = -0.27, 95% confidence interval (CI) = -0.364 to -0.172], with moderate negative correlations (summary = -0.52, 95% CI = -0.592 to -0.438). Meta-regression and subgroup analysis showed that types of cancer and study type were the source of heterogeneity. However, types of SS [actual SS, perceived social support (PSS), and others], source of actual SS, and source of PSS were not significant moderators.
To the best of our knowledge, this is the first systematic review and meta-analysis to quantitatively investigate the association between SS and FCR in Chinese cancer patients using β' and coefficients. The results re-emphasized that social workers should enhance the use of SS by cancer patients and establish a sound SS system by either implementing more relevant research or developing targeted policies. Based on meta-regression and subgroup analyses, moderators of the association between SS and FCR should also be studied closely as they may help identify patients in need. In addition, longitudinal research, as well as mixed research, should be conducted to more comprehensively explore the relationship between SS and FCR.
https://www.crd.york.ac.uk/prospero, identifier CRD42022332718.
通过回顾观察性研究的现有证据，定量分析社会支持（SS）与癌症复发恐惧（FCR）之间的关联。
对9个数据库从建库至2022年5月进行全面文献检索。纳入将SS和FCR均用作研究变量的观察性研究。使用R软件计算回归系数（β'）和相关系数（）。采用亚组分析来研究SS与FCR之间关系的程度以及各种形式的SS对癌症患者FCR的影响。
共纳入37项研究，涉及8190名参与者。SS显著降低FCR风险[合并β' = -0.27，95%置信区间（CI）= -0.364至-0.172]，呈中度负相关（汇总 = -0.52，95% CI = -0.592至-0.438）。Meta回归和亚组分析表明，癌症类型和研究类型是异质性来源。然而，SS类型[实际SS、感知社会支持（PSS）及其他]、实际SS来源和PSS来源并非显著的调节因素。
据我们所知，这是第一项使用β'和系数定量研究中国癌症患者中SS与FCR之间关联的系统评价和Meta分析。结果再次强调，社会工作者应加强癌症患者对SS的利用，并通过开展更多相关研究或制定针对性政策来建立完善的SS体系。基于Meta回归和亚组分析，还应密切研究SS与FCR之间关联的调节因素，因为它们可能有助于识别有需求的患者。此外，应开展纵向研究以及混合研究，以更全面地探索SS与FCR之间的关系。
