Malhotra Naveen, Joshi Muralidhar, Dey Samarjit, Sahoo Rajendra, Verma Sidharth, Asish K
Department of Cardiac Anaesthesia and Pain Management Centre, Pt. B. D. Sharma PGIMS Rohtak, Haryana, India.
Department of Anaesthesia and Pain Management, Virinchi Hospitals, Hyderabad, Telangana, India.
Indian J Anaesth. 2023 Jan;67(1):123-129. doi: 10.4103/ija.ija_31_23. Epub 2023 Jan 21.
Chronic pain presents as an unequalled challenge for physicians, owing to the complexity of biochemical and biological pathways involved in pain transmission and high variability of pain perception among individuals. Often, there is an inadequate response to conservative treatment, and opioid treatment has its own drawbacks, such as side effects and opioid dependence. Hence, novel strategies have evolved for the effective and safe management of chronic pain. Radiofrequency technique, regenerative biomaterial, platelet-rich plasma, mesenchymal stem cells, reactive oxygen species scavenger nanomaterial, ultrasound-guided interventional pain management procedures, endoscopic spinal procedures, vertebral augmentation therapy, and neuromodulation are some of the promising and upcoming modalities in the armamentarium of pain physicians.
慢性疼痛对医生来说是一个无与伦比的挑战，这是由于疼痛传递所涉及的生化和生物学途径的复杂性以及个体之间疼痛感知的高度变异性。通常，保守治疗的反应不足，而阿片类药物治疗也有其自身的缺点，如副作用和阿片类药物依赖。因此，已经开发出了新的策略来有效且安全地管理慢性疼痛。射频技术、再生生物材料、富血小板血浆、间充质干细胞、活性氧清除剂纳米材料、超声引导下的介入性疼痛管理程序、内镜脊柱手术、椎体强化治疗和神经调节是疼痛科医生现有手段中一些有前景且即将出现的方式。
