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Decoupling SERT-nNOS Interaction to Generate Fast-Onset Antidepressants.

作者信息

Ye Qing, Lin Si-Si, Ulrich Henning, Tang Yong

机构信息

International Joint Research Centre on Purinergic Signalling/School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, 05508, Brazil.

出版信息

Neurosci Bull. 2023 Aug;39(8):1327-1329. doi: 10.1007/s12264-023-01049-2. Epub 2023 Mar 28.

Abstract
摘要

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Ketamine triggers a switch in excitatory neuronal activity across neocortex.
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3
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Science. 2022 Oct 28;378(6618):390-398. doi: 10.1126/science.abo3566. Epub 2022 Oct 27.
5
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Nature. 2022 Aug;608(7922):368-373. doi: 10.1038/s41586-022-04993-7. Epub 2022 Jul 27.
6
Time for united action on depression: a Lancet-World Psychiatric Association Commission.
Lancet. 2022 Mar 5;399(10328):957-1022. doi: 10.1016/S0140-6736(21)02141-3. Epub 2022 Feb 15.
7
Electroconvulsive Therapy.
N Engl J Med. 2022 Feb 17;386(7):667-672. doi: 10.1056/NEJMra2034954.
8
Peripheral and central kynurenine pathway abnormalities in major depression.
Brain Behav Immun. 2022 Mar;101:136-145. doi: 10.1016/j.bbi.2022.01.002. Epub 2022 Jan 6.
9
Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications.
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