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神经源性疾病与下尿路功能障碍:妇科医生的处理方法建议。

Neurogenic Disorders and the Lower Urinary Tract Dysfunction: Proposed Approach for the Gynecologist.

机构信息

Urogynecology and Gynecological Perioperative Care Sector From Federal University of Uberlândia, Av Amazonas, 1595, Campus Umuarama, Uberlândia, Minas Gerais, 38411000, Brazil.

出版信息

Reprod Sci. 2023 Jul;30(7):2087-2091. doi: 10.1007/s43032-023-01213-z. Epub 2023 Mar 27.

DOI:10.1007/s43032-023-01213-z
PMID:36973580
Abstract

BACKGROUND

The scenario of the patient with neuropathies, which are related to urinary disorders, impacts the quality of life. Symptoms can lead to social isolation, impair activities of daily living, and shorten life expectancy. This study aims to make a practical and integrative review of current recommendations for the urogynecological approach of patients with neuropathy and urinary dysfunction.

METHODS

The authors searched for data on combinations of the terms "lower urinary tract symptoms" AND "neurogenic voiding dysfunction" from January 2012 to January 2022 in the following scientific databases: PUBMED, MEDLINE, EMBASE, and The Cochrane Library.

INCLUSION CRITERIA

randomized clinical trials, protocols from specialized societies and articles before that period, and according to clinical relevance.

EXCLUSION CRITERIA

case series or reports, expert opinions not endorsed by medical societies in the area.

RESULTS

From the 25 studies mentioned, 09 studies were selected according to pre-established criteria and qualitative analysis of relevance. The authors add 2 references for relevance in the area of ​​urogynecology and neurological diseases. According to the selected scientific references, the main neuropathies that can cause urinary dysfunction are CNS injuries such as stroke, spinal cord injury, meningomyelocele, and amyotrophic lateral sclerosis. Ten steps below were compiled to facilitate the gynecological approach, according to the researched literature.

CONCLUSION

It is important for the medical assistant to pay close attention to careful anamnesis and post-emptying urinary residual volume. The treatment in general addresses greater fluid intake, maneuvers to favor bladder emptying, medications, and/or intermittent self-catheterization. The approach of a multidisciplinary team can make a difference in the patient's prognosis and quality of life.

摘要

背景

与排尿障碍相关的神经病变患者的情况会影响生活质量。症状会导致社交孤立、影响日常生活活动,并缩短预期寿命。本研究旨在对目前神经源性排尿功能障碍患者的尿控处理方法的建议进行实用和综合的综述。

方法

作者在以下科学数据库中搜索了 2012 年 1 月至 2022 年 1 月期间与“下尿路症状”和“神经源性排尿功能障碍”相关的术语组合的数据:PUBMED、MEDLINE、EMBASE 和 Cochrane Library。

纳入标准

随机临床试验、专业协会的方案以及在此之前的相关文章。

排除标准

病例系列或报告、未经该领域医学协会认可的专家意见。

结果

在所提到的 25 项研究中,根据预先设定的标准和相关性的定性分析,有 09 项研究被选中。作者还添加了 2 篇与神经科疾病相关的尿控领域的相关性文献。根据所选的科学文献,可引起排尿功能障碍的主要神经病变是 CNS 损伤,如中风、脊髓损伤、脑脊膜膨出和肌萎缩侧索硬化症。根据研究文献,编译了 10 个便于妇科处理的步骤。

结论

医疗助理应密切关注详细的病史和排空后残余尿量。一般治疗方法是增加液体摄入、有利于膀胱排空的手法、药物治疗,和/或间歇性自我导尿。多学科团队的治疗方法可以改善患者的预后和生活质量。

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本文引用的文献

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The AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction: Treatment and Follow-up.AUA/SUFU 成人神经源性下尿路功能障碍指南:治疗与随访。
J Urol. 2021 Nov;206(5):1106-1113. doi: 10.1097/JU.0000000000002239. Epub 2021 Sep 8.
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The AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction: Diagnosis and Evaluation.AUA/SUFU 成人神经源性下尿路功能障碍指南:诊断与评估。
J Urol. 2021 Nov;206(5):1097-1105. doi: 10.1097/JU.0000000000002235. Epub 2021 Sep 8.
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Recommendations for evaluation of neurogenic bladder and bowel dysfunction after spinal cord injury and/or disease.
脊髓损伤和/或疾病后神经源性膀胱和肠功能障碍的评估建议。
J Spinal Cord Med. 2020 Mar;43(2):141-164. doi: 10.1080/10790268.2019.1706033.
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EAU/ESPU guidelines on the management of neurogenic bladder in children and adolescent part II operative management.EAU/ESPU 儿童和青少年神经源性膀胱管理指南 第二部分:手术治疗。
Neurourol Urodyn. 2020 Feb;39(2):498-506. doi: 10.1002/nau.24248. Epub 2019 Dec 3.
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EAU/ESPU guidelines on the management of neurogenic bladder in children and adolescent part I diagnostics and conservative treatment.EAU/ESPU 儿童和青少年神经源性膀胱管理指南 第一部分:诊断和保守治疗。
Neurourol Urodyn. 2020 Jan;39(1):45-57. doi: 10.1002/nau.24211. Epub 2019 Nov 13.
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Management of neurogenic bladder in patients with Parkinson's disease: A systematic review.帕金森病患者的神经源性膀胱管理:系统评价。
Neurourol Urodyn. 2019 Jan;38(1):31-62. doi: 10.1002/nau.23869. Epub 2018 Nov 8.
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Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder.抗毒蕈碱药物治疗膀胱过度活动症的基础和临床方面。
Pharmacol Ther. 2018 Sep;189:130-148. doi: 10.1016/j.pharmthera.2018.04.010. Epub 2018 Apr 27.
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Current and future international patterns of care of neurogenic bladder after spinal cord injury.脊髓损伤后神经源性膀胱的当前和未来国际护理模式。
World J Urol. 2018 Oct;36(10):1613-1619. doi: 10.1007/s00345-018-2277-8. Epub 2018 Mar 31.
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