Yévenes-Briones Humberto, Caballero Francisco Félix, Estrada-deLeón Daniela B, Struijk Ellen A, Mesas Arthur Eumann, Banegas José R, Rodríguez-Artalejo Fernando, Lopez-García Esther
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid.
CIBERESP (CIBER of Epidemiology and Public Health), Madrid, Spain.
Ear Hear. 2023;44(5):1182-1189. doi: 10.1097/AUD.0000000000001360. Epub 2023 Mar 28.
The duration and quality of sleep have been associated with multiple health conditions in adults. However, whether sleep duration and quality are associated with hearing loss (HL) is uncertain. The present study investigates the prospective association between duration and quality of sleep and HL.
This longitudinal analysis included 231,650 participants aged 38 to 72 years from the UK Biobank cohort, established in 2006-2010 in the United Kingdom. Duration and sleep complaints (snoring at night, daytime sleepiness, sleeplessness, difficulty getting up in the morning, and eveningness preference) were self-reported. HL was self-reported at baseline and during the follow-up.
Over a median follow-up of 4.19 (SD: 2.15) years, 6436 participants reported incident HL. In fully adjusted models, in comparison with sleeping between 7 and 8 hours a day, the adjusted hazard ratio (HR) (95% CI) associated with sleeping <7 hours a day was 1.01 (0.95 to 1.07), and for sleeping >8 hours a day was 0.98 (0.88 to 1.08). After adjustment for potential confounders, the HRs (95% confidence interval) of HL associated with having 1, 2, 3, and 4 to 5 vs. 0 sleep complaints were: 1.15 (1.05 to 1.27), 1.16 (1.05 to 1.28), 1.32 (1.19 to 1.47), and 1.49 (1.31 to 1.69), respectively; p for trend: <0.001. An increase in the number of sleep complaints was associated with higher risk of HL among participants with non-optimal sleep duration than among participants with optimal sleep duration.
In this large population-based study, poor sleep quality was associated with an increased risk of HL; however, sleep duration was not associated with risk.
睡眠时长和质量与成年人的多种健康状况相关。然而，睡眠时长和质量是否与听力损失（HL）相关尚不确定。本研究调查睡眠时长和质量与HL之间的前瞻性关联。
这项纵向分析纳入了英国生物银行队列中年龄在38至72岁之间的231,650名参与者，该队列于2006年至2010年在英国建立。睡眠时长和睡眠问题（夜间打鼾、白天嗜睡、失眠、早晨起床困难和晚睡倾向）均为自我报告。HL在基线和随访期间均为自我报告。
在中位随访4.19（标准差：2.15）年期间，6436名参与者报告了新发HL。在完全调整模型中，与每天睡眠7至8小时相比，每天睡眠<7小时的调整后风险比（HR）（95%置信区间）为1.01（0.95至1.07），每天睡眠>8小时的为0.98（0.88至1.08）。在调整潜在混杂因素后，与有0项睡眠问题相比，有1项、2项、3项以及4至5项睡眠问题的HL的HR（95%置信区间）分别为：1.15（1.05至1.27）、1.16（1.05至1.28）、1.32（1.19至1.47）和1.49（1.31至1.69）；趋势p值：<0.001。与睡眠时长最佳的参与者相比，睡眠时长非最佳的参与者中，睡眠问题数量增加与HL风险升高相关。
在这项基于大规模人群的研究中，睡眠质量差与HL风险增加相关；然而，睡眠时长与风险无关。
