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超声引导下梨状肌阻滞联合关节内注射皮质类固醇治疗髋骨关节炎:一项随机对照研究

Ultrasound-guided PENG block intraarticular corticosteroid injection in hip osteoarthritis: a randomised controlled study.

作者信息

Kose Selin Guven, Kose Halil Cihan, Celikel Feyza, Tulgar Serkan, Akkaya Omer Taylan

机构信息

Department of Pain Medicine, Health Science University Gaziler Physical Therapy and Rehabilitation Training and Research Hospital, Ankara, Turkiye.

Department of Pain Medicine, Health Science University Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkiye.

出版信息

Korean J Pain. 2023 Apr 1;36(2):195-207. doi: 10.3344/kjp.22325.

Abstract

BACKGROUND

This study aimed to compare the effectiveness of the pericapsular nerve group (PENG) block and intra-articular injection (IAI) of steroid-bupivacaine in the treatment of hip osteoarthritis (OA).

METHODS

After randomization, patients received either a PENG block or IAI under ultrasound-guidance. Clinical evaluations were recorded at baseline, day 1, and weeks 1, 4, and 8 post-intervention. The numerical rating scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), Harris Hip Scale (HHS) scores, pain medication use determined by a quantitative analgesic questionnaire, and patient satisfaction were evaluated.

RESULTS

Sixty patients were included in this study. NRS scores improved significantly for both groups during the follow-up compared to pretreatment ( < 0.001), with better pain scores for the PENG group ( < 0.001) at day 1 with larger effect size (Cohen's d = 4.62), and IAI group at 4 (Cohen's d = 5.15) and 8 (Cohen's d = 4.33) weeks ( < 0.001). There was no significant difference in pain medication consumption ( = 0.499) and patient satisfaction ( = 0.138) between groups. Patients in the IAI group experienced significant improvement in HHS (Cohen's d = 2.16, = 0.007) and WOMAC (Cohen's d = 1.02, = 0.036) scores at 8 weeks compared to the PENG group.

CONCLUSIONS

The ultrasound-guided PENG block provides effective pain relief which improves functionality and quality of life in hip OA patients up to 2 months. The PENG block can be considered an easy, safe, and useful alternative treatment modality for hip OA.

摘要

背景

本研究旨在比较关节周围神经群(PENG)阻滞与关节内注射(IAI)类固醇-布比卡因治疗髋骨关节炎(OA)的效果。

方法

随机分组后,患者在超声引导下接受PENG阻滞或IAI。在基线、第1天以及干预后第1、4和8周记录临床评估结果。评估数字评分量表(NRS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、Harris髋关节评分(HHS)、通过定量镇痛问卷确定的止痛药物使用情况以及患者满意度。

结果

本研究纳入了60例患者。与治疗前相比,两组在随访期间NRS评分均显著改善(<0.001),PENG组在第1天疼痛评分更好(<0.001),效应量更大(Cohen's d = 4.62),IAI组在第4周(Cohen's d = 5.15)和第8周(Cohen's d = 4.33)疼痛评分更好(<0.001)。两组之间止痛药物消耗量(=0.499)和患者满意度(=0.138)无显著差异。与PENG组相比,IAI组患者在第8周时HHS评分(Cohen's d = 2.16,=0.007)和WOMAC评分(Cohen's d = 1.02,=0.036)有显著改善。

结论

超声引导下的PENG阻滞可有效缓解疼痛,改善髋OA患者长达2个月的功能和生活质量。PENG阻滞可被视为髋OA一种简便、安全且有用的替代治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b76e/10043791/2cfd561a4b1e/kjp-36-2-195-f5.jpg

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