Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Health Department of Longgang District Maternity & Child Healthcare Hospital of Shenzhen City, Shenzhen, China.
Int J Environ Health Res. 2024 Apr;34(4):1961-1976. doi: 10.1080/09603123.2023.2196056. Epub 2023 Mar 27.
There is little research on the relationship between phthalates exposure and sleep problems in adult females, with existing studies only assessing the association between exposure to individual phthalates with sleep problems. We aimed to analyse the relationship between phthalates and sleep problems in 1366 US females aged 20 years and older from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) by age stratification. Multivariate logistic regression showed that the fourth quartile of MECPP increased the risk of sleep problems in females aged 20-39 compared with the reference quartile (OR: 1.87, 95% CI: 1.14, 3.08). The WQS index was significantly associated with the sleep problems in females aged 20-39. In the BKMR, a positive overall trend between the mixture and sleep problems in females aged 20-39. In this study, we concluded that phthalates might increase the risk of sleep problems in females aged 20-39.
关于邻苯二甲酸酯暴露与成年女性睡眠问题之间的关系，研究甚少，现有研究仅评估了接触个别邻苯二甲酸酯与睡眠问题之间的关联。我们旨在通过年龄分层，分析 2011-2014 年美国国家健康和营养检查调查（NHANES）中 1366 名年龄在 20 岁及以上的美国女性中邻苯二甲酸酯与睡眠问题之间的关系。多变量逻辑回归显示，与参考四分位相比，MECPP 的第四四分位数增加了 20-39 岁女性睡眠问题的风险（OR：1.87，95%CI：1.14，3.08）。WQS 指数与 20-39 岁女性的睡眠问题显著相关。在 BKMR 中，20-39 岁女性混合物与睡眠问题之间存在正相关的总体趋势。在这项研究中，我们得出结论，邻苯二甲酸酯可能会增加 20-39 岁女性睡眠问题的风险。
