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腹直肌鞘阻滞与局部麻醉浸润在小儿腹腔镜腹股沟疝修补术中的比较:一项随机对照试验。

Rectus sheath block versus local anesthetic infiltration in pediatric laparoscopic inguinal hernia repair: a randomized controlled trial.

机构信息

Department of Anesthesiology.

Department of Emergency Medicine, Shengjing Hospital of China Medical University, Heping District, Shenyang, Liaoning Province, People's Republic of China.

出版信息

Int J Surg. 2023 Apr 1;109(4):716-722. doi: 10.1097/JS9.0000000000000265.

Abstract

BACKGROUND

Rectus sheath block (RSB) and local anesthetic infiltration (LAI) are used for postoperative analgesia in pediatric laparoscopic inguinal hernia repair. However, whether the analgesic effect of RSB is superior to LAI remains unclear. The authors hypothesized that RSB would reduce opioid consumption in patients.

METHODS

Patients aged 3-14 years scheduled for laparoscopic inguinal hernia repair were randomly allocated to the RSB, local anesthetic infiltration high concentration (LAIHC), local anesthetic infiltration low concentration (LAILC), or control groups. Preoperatively, they received 0.4 ml/kg of 0.25% ropivacaine (RSB), 0.4 ml/kg of 0.25% ropivacaine (LAILC), or 0.2 ml/kg of 0.5% ropivacaine(LAIHC), and 0.2 ml/kg of normal saline (control). The primary outcome was equivalent morphine consumption.

RESULTS

The authors analyzed 136 patients (RSB, 33; LAIHC, 34; LAILC, 35; control, 34). Intraoperative morphine equivalent consumption was lower in the RSB group [0.115 (0.107-0.123)] than in the LAIHC [0.144 (0.137-0.151)], LAILC [0.141 (0.134-0.149)], and control [0.160 (0.151-0.170)] groups ( P <0.001). In the post-anesthesia care unit, morphine equivalent consumption differed between the RSB [0.018 (0.010-0.027)], LAIHC [0.038 (0.028-0.049)], LAILC [0.056 (0.044-0.067)], and control [0.074 (0.063-0.084)] groups ( P <0.001). The rescue morphine equivalent consumption did not differ significantly between the RSB [0.015 (0.007-0.023)] and LAIHC [0.019 (0.010-0.029)] groups, which were lower than that in the control group [0.037 (0.029-0.045)] ( P =0.001).

CONCLUSIONS

RSB can provide effective analgesia for pediatric laparoscopic inguinal hernia repair, with better effectiveness than that of LAI at the same dose.

摘要

背景

腹直肌鞘阻滞(RSB)和局部麻醉浸润(LAI)用于小儿腹腔镜腹股沟疝修补术后镇痛。然而,RSB 的镇痛效果是否优于 LAI 尚不清楚。作者假设 RSB 会减少患者的阿片类药物消耗。

方法

择期行腹腔镜腹股沟疝修补术的 3-14 岁患儿随机分配至 RSB 组、高浓度局部麻醉浸润(LAIHC)组、低浓度局部麻醉浸润(LAILC)组或对照组。术前,他们分别接受 0.4ml/kg 的 0.25%罗哌卡因(RSB)、0.4ml/kg 的 0.25%罗哌卡因(LAILC)或 0.2ml/kg 的 0.5%罗哌卡因(LAIHC)和 0.2ml/kg 的生理盐水(对照组)。主要结局为等效吗啡消耗量。

结果

作者分析了 136 例患者(RSB 组 33 例,LAIHC 组 34 例,LAILC 组 35 例,对照组 34 例)。术中吗啡等效消耗量在 RSB 组[0.115(0.107-0.123)]低于 LAIHC 组[0.144(0.137-0.151)]、LAILC 组[0.141(0.134-0.149)]和对照组[0.160(0.151-0.170)](P<0.001)。在麻醉后护理单元,RSB 组[0.018(0.010-0.027)]、LAIHC 组[0.038(0.028-0.049)]、LAILC 组[0.056(0.044-0.067)]和对照组[0.074(0.063-0.084)]之间的吗啡等效消耗量存在差异(P<0.001)。RSB 组[0.015(0.007-0.023)]和 LAIHC 组[0.019(0.010-0.029)]的解救吗啡等效消耗量与对照组[0.037(0.029-0.045)]相比无显著差异(P=0.001)。

结论

RSB 可为小儿腹腔镜腹股沟疝修补术提供有效镇痛,其在相同剂量下的效果优于 LAI。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92ea/10389327/82367c59849f/js9-109-0716-g001.jpg

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