Department of Oral and Maxillofacial Surgery, Army Hospital Hamburg, Hamburg, Germany;
Department of Oral and Maxillofacial Surgery, Army Hospital Hamburg, Hamburg, Germany.
Anticancer Res. 2023 Apr;43(4):1869-1871. doi: 10.21873/anticanres.16342.
Tumors of the oral cavity must be differentiated into benign and malignant. Rare tumors must also be considered throughout the differential diagnosis when dealing with pathologic changes in the oral mucosa. Examples of rare benign tumors within the oral cavity are solitary fibrous tumors (SFTs). In recent years, individual case reports of SFTs in the oral cavity have been published showing a rising incidence of this rare entity.
The present case report describes the occurrence of a subtype of SFT in the right buccal mucosa, the so-called giant cell angiofibroma (GCA). Histopathologically, GCA are distinguishable from SFT (NOS) by pseudovascular spaces lined by multinucleated giant cells. GCA generally shows a benign tumor behavior. The treatment of choice was surgical excision through an intraoral approach.
To the best of our knowledge, this is one of a few reports of GCA arising in the buccal mucosa.
口腔肿瘤必须分为良性和恶性。在处理口腔黏膜的病理变化时,鉴别诊断中还必须考虑到罕见肿瘤。口腔内罕见良性肿瘤的例子是孤立性纤维瘤(SFT)。近年来,口腔 SFT 的个别病例报告表明,这种罕见实体的发病率正在上升。
本病例报告描述了右颊黏膜发生 SFT 的一种亚型,即所谓的巨细胞血管纤维瘤(GCA)。组织病理学上,GCA 通过由多核巨细胞衬里的假血管腔与 SFT(NOS)区分开来。GCA 通常表现出良性肿瘤行为。首选的治疗方法是通过口腔入路进行手术切除。
据我们所知,这是少数几例发生在颊黏膜的 GCA 报告之一。