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[Transplacental effect of methylcobalamine on the growth of embryonic mouse kidney tissue in organotypic cultivation].

作者信息

Golenko O D, Ryzhova N I

出版信息

Biull Eksp Biol Med. 1986 Apr;101(4):471-4.

PMID:3697496
Abstract

Transplacental growth-stimulating effect of the Cbl-coenzyme methylcobalamine (MeCbl) was revealed in organ cultures of embryonic kidney tissue in DBA/2 mice. MeCbl improved the survival of embryonic kidney explants and decreased the incidence of degenerative damage in cultures. The frequency of regeneration development was 30%. Hyperplastic epithelial changes were much more marked after transplacental MeCbl administration (71.8%), than in the control (9.0%).

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