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具有网状青斑样外观的结节病。

Sarcoidosis with the livedo reticularis-like appearance.

作者信息

Wang Yu-Feng, Song Chun-Xiao, Tan Cheng

机构信息

Affiliated Hospital of Nanjing University of Chinese Medicine.

出版信息

Sarcoidosis Vasc Diffuse Lung Dis. 2023 Mar 28;40(1):e2023007. doi: 10.36141/svdld.v40i1.12011.

DOI:10.36141/svdld.v40i1.12011
PMID:36975059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10099652/
Abstract

Sarcoidosis is a multisystem inflammatory disease manifesting as noncaseating epithelioid cell granulomas. 25 to 30% of individuals with systemic sarcoidosis show variable cutaneous manifestations. A 59-year-old female was seen with reticular purplish-red nodules and plaques on the legs for three months. A skin biopsy of the livedo area revealed non-caseating epithelioid cell granulomas surrounding blood vessels in the dermis. She was diagnosed with sarcoidosis livedo, and cutaneous lesions subsided with oral prednisone. Sarcoidosis livedo (SL) assumes a uncommon livedo reticularis-like presentation. This is the first Chinese patient with SL, and more patients are needed to unveil the unique characters of SL.

摘要

结节病是一种多系统炎症性疾病，表现为非干酪样上皮样细胞肉芽肿。25%至30%的系统性结节病患者有不同的皮肤表现。一名59岁女性因腿部出现网状紫红色结节和斑块3个月前来就诊。对青斑区域进行皮肤活检，结果显示真皮层血管周围有非干酪样上皮样细胞肉芽肿。她被诊断为结节病性青斑，口服泼尼松后皮肤病变消退。结节病性青斑（SL）呈现出一种罕见的类似网状青斑的表现。这是首例中国的SL患者，需要更多患者来揭示SL的独特特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/b8d137503614/SVDLD-40-7-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/4f18ff6d8594/SVDLD-40-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/de456186684c/SVDLD-40-7-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/b8d137503614/SVDLD-40-7-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/4f18ff6d8594/SVDLD-40-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/de456186684c/SVDLD-40-7-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f70/10099652/b8d137503614/SVDLD-40-7-g003.jpg

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本文引用的文献

1
Clinical Characteristics of Sarcoidosis in Asian Population: A 14-year Single Center Retrospective Cohort Study from Thailand.亚洲人群中结节病的临床特征：来自泰国的一项为期 14 年的单中心回顾性队列研究。
Sarcoidosis Vasc Diffuse Lung Dis. 2020;37(4):e2020011. doi: 10.36141/svdld.v37i4.10136. Epub 2020 Dec 16.
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Cutaneous Sarcoidosis.皮肤结节病。
Semin Respir Crit Care Med. 2020 Oct;41(5):689-699. doi: 10.1055/s-0040-1713130. Epub 2020 Jun 27.
3
Cutaneous sarcoidosis with livedo-like manifestation.伴有类青斑样表现的皮肤结节病。
An Bras Dermatol. 2019 Oct 17;94(4):493-494. doi: 10.1590/abd1806-4841.20198173. eCollection 2019.
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Granulomatous cutaneous sarcoidosis: diagnosis, relationship to systemic disease, prognosis and treatment.肉芽肿性皮肤结节病：诊断、与全身性疾病的关系、预后及治疗
Sarcoidosis Vasc Diffuse Lung Dis. 2013 Dec 17;30(4):268-81.
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A case of sarcoidosis with livedo.一例伴有网状青斑的结节病。
Int J Dermatol. 2009 Nov;48(11):1217-21. doi: 10.1111/j.1365-4632.2009.04123.x.