Kim Joong Ho, Uh Ji An, Kim Ho Sung, Lee Soo Kyung, Kim Myoung Shin, Lee Un Ha
Department of Dermatology, Inje University Sanggye Paik Hospital, Seoul, Korea.
Clin Exp Vaccine Res. 2022 Sep;11(3):298-301. doi: 10.7774/cevr.2022.11.3.298. Epub 2022 Sep 30.
The cutaneous appearance of transient or persistent livedo reticularis is characterized by violaceous, mottled, ring-shaped interconnecting lesions that form a reticular or net-like pattern. It can occur physiologically in response to cold exposure, such as in cutis marmorata, but can also be induced by pathological conditions such as vascular obliterans or venodilation. We report two cases of livedo reticularis that occurred on the lower limbs of two patients post ChAdOx1 nCoV-19 vaccination. As the patients had no other likely causes of livedo reticularis, the reticular skin lesions were suspected to occur in association with the ChAdOx1 nCoV-19 vaccination. Livedo reticularis is an uncommon adverse reaction, with few cases being reported post ChAdOx1 nCoV-19 vaccination.
短暂性或持续性网状青斑的皮肤表现特征为紫罗兰色、斑驳状、环形相互连接的皮损，形成网状或类似网状的图案。它可在生理上因暴露于寒冷而出现，如大理石样皮肤，但也可由血管闭塞或静脉扩张等病理状况诱发。我们报告了两例在接种ChAdOx1 nCoV-19疫苗后发生于两名患者下肢的网状青斑病例。由于患者没有其他可能导致网状青斑的原因，故怀疑网状皮肤损害与ChAdOx1 nCoV-19疫苗接种有关。网状青斑是一种罕见的不良反应，ChAdOx1 nCoV-19疫苗接种后报告的病例很少。
