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拔牙手术中使用的多丝和单丝缝合材料的力学性能及抗微生物性能的比较分析

Comparative Analysis of Mechanical Properties and Microbiological Resistance of Polyfilament and Monofilament Suture Materials Used in the Operation "Tooth Extraction".

作者信息

Pcheliakov Alexey A, Diachkova Ekaterina Yu, Vasil'ev Yuriy L, Svitich Oxana A, Poddubikov Alexander V, Evlashin Stanislav A, Volel Beatrice A, Bakhmet Anastasia A, Klochkova Svetlana V, Velichko Ellina V, Tiunova Natalia, Tarasenko Svetlana V

机构信息

Department of Oral Surgery of Borovsky Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya St. Bldg. 8\2, 119435 Moscow, Russia.

Department of Operative Surgery and Topographic Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya St. Bldg. 8\2, 119435 Moscow, Russia.

出版信息

Biomimetics (Basel). 2023 Mar 22;8(1):129. doi: 10.3390/biomimetics8010129.

Abstract

In surgical dentistry, suture material is the only foreign body that remains in the tissues after surgery, and it can lead to several negative reactions, for example, infection of the wound. The purpose of this study was to compare the mechanical properties and microbiological resistance of mono- and polyfilament suture materials used in tooth extraction operations. The study of elongation and knot force was carried out on an Instron 5969 Dual Column Testing System device. The capillarity of the materials was studied on a setup assembled by the authors manually by immersing the ends of the filaments in a colored manganese solution. A microbiological study was carried out on the threads taken for the experiment immediately after wound suturing, and on day 7, at which time they were removed. The comparison was made according to Rothia mucilaginosa, Streptococcus sanguinis, Staphylococcus epidermidis. Results: monofilament suture materials (Prolene and Glycolon), after calculating the Kruskal-Wallis and Mann-Whitney indices, showed better performance in all experiments compared to polyfilament sutures (Vicryl and PGA). In capillarity comparison, there was a significant difference between groups ( = 0.00018). According to the sum of the results of three microbiological studies on day 7, monofilament suture materials absorbed less of the studied bacteria on their surface compared to the polyfilament ones ( < 0.05). Conclusions: Of the studied suture materials, Prolene had the best microbiological resistance and good mechanical properties.

摘要

在口腔外科手术中,缝合材料是手术后留在组织中的唯一异物,它可能会引发多种不良反应,例如伤口感染。本研究的目的是比较用于拔牙手术的单丝和多丝缝合材料的机械性能和抗微生物性能。在英斯特朗5969双柱测试系统设备上进行了伸长率和结力的研究。通过将细丝末端浸入有色锰溶液中,在作者手动组装的装置上研究了材料的毛细作用。在伤口缝合后立即对用于实验的缝线进行微生物学研究,并在第7天(此时将缝线拆除)进行研究。根据粘液罗氏菌、血链球菌、表皮葡萄球菌进行比较。结果:在计算克鲁斯卡尔 - 沃利斯和曼 - 惠特尼指数后,单丝缝合材料(普理灵和甘醇)在所有实验中均比多丝缝合线(薇乔和聚乙醇酸)表现更好。在毛细作用比较中,各组之间存在显著差异( = 0.00018)。根据第7天三项微生物学研究的结果总和,与多丝缝合材料相比,单丝缝合材料表面吸收的研究细菌较少( < 0.05)。结论:在所研究的缝合材料中,普理灵具有最佳的抗微生物性能和良好的机械性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e577/10046333/d10063a624a5/biomimetics-08-00129-g001.jpg

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