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猴痘:成人猴痘的诊断、预防与管理

Mpox (monkeypox): Diagnosis, prevention, and management in adults.

作者信息

Jarrell Lynda, Perryman Kashiris

出版信息

Nurse Pract. 2023 Apr 1;48(4):13-20. doi: 10.1097/01.NPR.0000000000000025.

Abstract

Mpox (formerly "monkeypox") is a viral zoonosis that presents similarly to smallpox but is less contagious and causes less severe disease. Mpox may be transmitted from infected animals to humans through direct contact or a scratch or bite. Human-to-human transmission occurs through direct contact, respiratory droplets, and fomites. Two vaccines, JYNNEOS® and ACAM2000®, are currently available for postexposure prophylaxis as well as for prevention in certain populations at high risk for mpox. Most cases of mpox are self-limited; however, tecovirimat, brincidofovir, and cidofovir are available as treatments for at-risk populations.

摘要

猴痘(原称“猴天花”)是一种病毒性人畜共患病,其症状与天花相似,但传染性较低,病情也较轻。猴痘可通过直接接触、抓伤或咬伤从受感染动物传播给人类。人际传播则通过直接接触、呼吸道飞沫和污染物实现。目前有两种疫苗,即JYNneos®和ACAM2000®,可用于暴露后预防以及在某些猴痘高危人群中进行预防。大多数猴痘病例是自限性的;然而,tecovirimat、brincidofovir和西多福韦可用于高危人群的治疗。

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