Department of Food Science and Technology, Faculty of Agricultural Sciences, University of Guilan, Rasht, Iran.
Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.
Crit Rev Food Sci Nutr. 2024;64(22):7804-7835. doi: 10.1080/10408398.2023.2192281. Epub 2023 Mar 28.
Gut microbiota (GMB) in humans plays a crucial role in health and diseases. Diet can regulate the composition and function of GMB which are associated with different human diseases. Dietary fibers can induce different health benefits through stimulation of beneficial GMB. β-glucans (BGs) as dietary fibers have gained much interest due to their various functional properties. They can have therapeutic roles on gut health based on modulation of GMB, intestinal fermentation, production of different metabolites, and so on. There is an increasing interest in food industries in commercial application of BG as a bioactive substance into food formulations. The aim of this review is considering the metabolizing of BGs by GMB, effects of BGs on the variation of GMB population, influence of BGs on the gut infections, prebiotic effects of BGs in the gut, in vivo and in vitro fermentation of BGs and effects of processing on BG fermentability.
人类肠道微生物群（GMB）在健康和疾病中起着至关重要的作用。饮食可以调节 GMB 的组成和功能，而 GMB 与不同的人类疾病有关。膳食纤维可以通过刺激有益的 GMB 来诱导不同的健康益处。β-葡聚糖（BGs）作为膳食纤维，由于其各种功能特性而备受关注。它们可以通过调节 GMB、肠道发酵、产生不同代谢物等方式对肠道健康发挥治疗作用。食品工业对将 BG 作为生物活性物质应用于食品配方的商业应用越来越感兴趣。本综述的目的是考虑 GMB 对 BG 的代谢、BG 对 GMB 种群变化的影响、BG 对肠道感染的影响、BG 在肠道中的益生元作用、BG 的体内和体外发酵以及加工对 BG 可发酵性的影响。
