放疗在德国 Merkel 细胞癌治疗更新 S2k 指南中的作用。
The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma.
机构信息
Dept. of Radiation Oncology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Universitätsklinik für Strahlentherapie, Universitätsklinikum Halle/Saale, Ernst-Grube-Str. 40, 06120, Halle/Saale, Germany.
出版信息
Strahlenther Onkol. 2023 May;199(5):433-435. doi: 10.1007/s00066-023-02068-8. Epub 2023 Mar 28.
Abstract
Merkel cell carcinoma (MCC) is a radiosensitive tumor and the role of radiotherapy in the management of this disease was newly defined in the recently published update of the S2k guideline on Merkel cell carcinoma of the Association of Scientific Medical Societies in Germany (AWMF). While adjuvant radiotherapy of the tumor bed is broadly recommended, irradiation of the regional nodal region can be performed in patients with negative sentinel lymph nodes and high-risk factors. In patients with positive sentinel lymph nodes, it is an alternative to completion lymphadenectomy. The standard dose for adjuvant radiotherapy remains 50 Gy.
摘要
默克尔细胞癌（Merkel cell carcinoma，MCC）是一种对放疗敏感的肿瘤，德国科学医学协会联合会（AWMF）最近发布的默克尔细胞癌 S2k 指南更新版中重新定义了放疗在该疾病治疗中的作用。虽然广泛推荐对肿瘤床进行辅助放疗，但对于前哨淋巴结阴性且存在高危因素的患者，可以对区域淋巴结区域进行照射。对于前哨淋巴结阳性的患者，放疗是完成淋巴结清扫术的一种替代方法。辅助放疗的标准剂量仍为 50Gy。
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