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近端胃迷走神经切断术还是迷走神经干切断术加引流术治疗慢性十二指肠溃疡?

Proximal gastric vagotomy or truncal vagotomy and drainage for chronic duodenal ulcer?

作者信息

Clark C G, Fresini A, Araujo J G, Boulos P B

出版信息

Br J Surg. 1986 Apr;73(4):298-300. doi: 10.1002/bjs.1800730417.

Abstract

A comparison has been made between truncal vagotomy and drainage (TVD) and proximal gastric vagotomy (PGV) performed electively for chronic duodenal ulceration from 1968 to 1981 in 209 and 272 patients respectively. The morbidity was 23 per cent after TVD and 19.8 per cent after PGV, with a mortality of 0.5 per cent and 0.4 per cent respectively. Of 163 patients in the former group and 253 patients in the latter group the follow-up was an average of 5.7 and 6.2 years respectively; 128 patients (78.5 per cent) and 198 (78.3 per cent) respectively had a good functional result, graded as Visick I and II, but 35 (21.7 per cent) and 55 (21.7 per cent), respectively, had a poor result owing to recurrent ulceration in 23 (14.1 per cent) after TVD and 44 (17.4 per cent) after PGV. These results were not statistically different. The frequency of diarrhoea was 23 per cent and dumping 6.8 per cent after TVD which was significantly reduced to 2.0 per cent (P less than 0.005) and 1.2 per cent (P less than 0.025), respectively, after PGV. However, only five patients (3.0 per cent) had severe symptoms from diarrhoea and two (1.2 per cent) from dumping after TVD. Both operations seem to carry an equal incidence of unsatisfactory results, though for slightly different reasons it might be concluded that both procedures have an equal degree of acceptability.

摘要

1968年至1981年期间,分别对209例和272例慢性十二指肠溃疡患者进行了选择性的迷走神经干切断术加引流术(TVD)和近端胃迷走神经切断术(PGV),并进行了比较。TVD术后发病率为23%,PGV术后为19.8%,死亡率分别为0.5%和0.4%。前一组163例患者和后一组253例患者的平均随访时间分别为5.7年和6.2年;分别有128例(78.5%)和198例(78.3%)功能恢复良好,评定为Visick I级和II级,但分别有35例(21.7%)和55例(21.7%)效果不佳,原因是TVD术后23例(14.1%)和PGV术后44例(17.4%)出现复发性溃疡。这些结果在统计学上无差异。TVD术后腹泻发生率为23%,倾倒综合征发生率为6.8%,PGV术后分别显著降至2.0%(P<0.005)和1.2%(P<0.025)。然而,TVD术后只有5例(3.0%)患者有严重腹泻症状,2例(1.2%)有倾倒综合征症状。两种手术的不满意结果发生率似乎相同,尽管原因略有不同,但可以得出结论,两种手术的可接受程度相同。

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