使用聚乙二醇实现切断的神经轴突重新连接。
Reconnection of severed nerve axons with polyethylene glycol.
作者信息
Bittner G D, Ballinger M L, Raymond M A
出版信息
Brain Res. 1986 Mar 5;367(1-2):351-5. doi: 10.1016/0006-8993(86)91617-3.
PMID:3697710
Abstract
Severed medial giant axons in crayfish can be rejoined in vitro with polyethylene glycol (PEG) to produce axoplasmic continuity and through transmission of action potentials. Severed axon-like processes of a mammalian neuroblastoma/glioma cell line seem to be rejoined to the cell body using PEG in tissue culture. Our data suggest that PEG might be used to rejoin severed axons in vivo in various organisms.
摘要
小龙虾中被切断的内侧巨轴突可在体外与聚乙二醇（PEG）重新连接，以实现轴浆连续性并通过动作电位的传导。在组织培养中，使用PEG似乎可将哺乳动物神经母细胞瘤/胶质瘤细胞系中被切断的轴突样突起重新连接到细胞体。我们的数据表明，PEG可用于在体内重新连接各种生物体中被切断的轴突。
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