Tani Akiyoshi, Suzuki Ryohei, Matsukata Satoshi, Nakamura Atsushi, Nuruki Takaomi
The TRVA Animal Medical Center, Tokyo Jonan Regional Veterinary Medicine Promotional Association, Tokyo 158-0081, Japan.
Laboratory of Veterinary Internal Medicine, School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Tokyo 180-8602, Japan.
Vet Sci. 2023 Mar 19;10(3):232. doi: 10.3390/vetsci10030232.
Cats urgently visit emergency hospitals due to respiratory distress, and the chief cause is cardiogenic pulmonary edema (CPE). Although cats with CPE were frequently encountered in clinics, the prognostic factors were poorly reported. The objective of this retrospective study was to investigate the association of physical examination and venous blood gas parameters with the survival of cats with CPE in an emergency hospital. Thirty-six cats with CPE were ultimately included in the present study, and eight of them died within 12 h after their presentation to our hospital. Statistical analyses of clinical parameters between cats that died within 12 h and those that survived for 12 h were conducted using Mann-Whitney U test with Bonferroni correction. Cats that died within 12 h had significantly lower rectal temperatures and higher PvCO than those that did not die within 12 h. Moreover, hypotension and vasoconstrictor use were related to death within 12 h of presentation and higher PvCO. These findings indicated the prognostic utility of body temperature and PvCO, and the association between hypercapnia and the severity of CPE or hypotension. A large number of prospective studies should be performed to validate these results.
猫因呼吸窘迫紧急前往急诊医院,主要原因是心源性肺水肿(CPE)。尽管临床上经常遇到患有CPE的猫,但关于预后因素的报道却很少。这项回顾性研究的目的是调查急诊医院中患有CPE的猫的体格检查和静脉血气参数与生存情况之间的关联。本研究最终纳入了36只患有CPE的猫,其中8只在入院后12小时内死亡。使用经Bonferroni校正的Mann-Whitney U检验对在12小时内死亡的猫和存活12小时的猫的临床参数进行统计分析。在12小时内死亡的猫的直肠温度显著低于未在12小时内死亡的猫,且其静脉血二氧化碳分压(PvCO)更高。此外,低血压和使用血管收缩剂与入院后12小时内死亡及更高的PvCO有关。这些发现表明体温和PvCO对预后有参考价值,以及高碳酸血症与CPE严重程度或低血压之间的关联。应进行大量前瞻性研究以验证这些结果。