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允许骺板生长对髋关节骨滑脱症的益处

Who Benefits From Allowing the Physis to Grow in Slipped Capital Femoral Epiphysis?

机构信息

The Children's Hospital at Westmead, Sydney, NSW.

The University of Sydney, Sydney, New South Wales, Australia.

出版信息

J Pediatr Orthop. 2023 Jul 1;43(6):e427-e432. doi: 10.1097/BPO.0000000000002407. Epub 2023 Mar 27.

Abstract

BACKGROUND

The globally acknowledged treatment for mild to moderate slipped capital femoral epiphysis (SCFE) is single screw in situ fixation, also used for prophylactic contralateral fixation. The Free-Gliding Screw (FG; Pega Medical) is a 2-part free-extending screw system designed to allow the growth of the proximal femur. We aimed to analyze the relationship between skeletal maturity and potential growth of the proximal physis and remodeling of the femoral neck using this implant.

MATERIALS AND METHODS

Females below 12 years and males below 14 years undergoing in situ fixation for stable SCFE or prophylactic fixation were treated using the implant. Three elements of the modified Oxford Bone (mOB 3 ) score were used to measure maturity (triradiate cartilage, head of the femur, and greater trochanter). Radiographs were analyzed immediately postoperatively and at a minimum of 2 years for a change in screw length, posterior-sloping angle, articulotrochanteric distance, α angle, and head-neck offset.

RESULTS

The study group comprised 30 (F:M=12:18) of 39 hips treated with SCFE and 22 (F:M=13:9) of 29 hips managed prophylactically using the free-Gliding screw. In the therapeutic group, chronologic age was a less valuable predictor of future screw lengthening than mOB 3 . An mOB 3 of ≤13 predicted future growth of >6 mm but did not reach statistical significance ( P =0.07). Patients with open triradiates showed a mean screw lengthening of 6.6 mm compared with those with closed triradiates (4.0 mm), but this did not reach significance ( P =0.12). In those with mOB 3 ≤13, the α angle reduced significantly ( P <0.01) and the head-neck offset increased significantly, suggesting remodeling. There was no change in these parameters when mOB 3 ≥14. In the prophylactic group, change in screw length was significant with mOB 3 of ≤13 (mean=8.0 mm, P <0.05), as was the presence of an open triradiate cartilage (mean=7.7 mm, P <0.05). In both cohorts, posterior-sloping angle and articulotrochanteric distance did not change, indicating no slip progression in either treatment or prophylactic groups and minimal effect on the proximal physeal growth relative to the greater trochanter.

CONCLUSIONS

Growing screw constructs can halt slip progression while allowing proximal femoral growth in young patients with SCFE. Ongoing growth is better when the implant is used for prophylactic fixation. The results in treated SCFE need to be expanded to demonstrate a clinically meaningful cut-off for significant growth, but SCFE patients with an open triradiate remodel significantly more than those where it is closed.

LEVEL OF EVIDENCE

Level III-retrospective comparative study.

摘要

背景

对于轻度至中度股骨头骨骺滑脱(SCFE),全球公认的治疗方法是单枚螺钉原位固定,也用于预防性对侧固定。自由滑动螺钉(FG;Pega Medical)是一种 2 部分自由延伸螺钉系统,旨在允许股骨近端生长。我们旨在使用该植入物分析骨骼成熟度与近端骨骺潜在生长和股骨颈重塑之间的关系。

材料和方法

12 岁以下女性和 14 岁以下男性因稳定型 SCFE 或预防性固定而行原位固定者采用该植入物治疗。改良牛津骨(mOB 3 )评分的 3 个要素用于测量成熟度(三射线软骨、股骨头和大转子)。术后立即和至少 2 年时分析 X 线片,以评估螺钉长度、后倾角度、关节突-转子距离、α 角和头-颈偏移的变化。

结果

研究组包括 39 髋 SCFE 治疗中的 30 髋(F:M=12:18)和 29 髋预防性使用自由滑动螺钉治疗的 22 髋(F:M=13:9)。在治疗组中,骨龄是未来螺钉延长的预测值不如 mOB 3 可靠。mOB 3 ≤13 预测未来生长>6mm,但无统计学意义(P=0.07)。三射线软骨开放的患者平均螺钉延长 6.6mm,而三射线软骨闭合的患者平均螺钉延长 4.0mm,但无统计学意义(P=0.12)。在 mOB 3 ≤13 的患者中,α 角显著降低(P<0.01),头-颈偏移显著增加,提示重塑。当 mOB 3 ≥14 时,这些参数没有变化。在预防性组中,mOB 3 ≤13 时螺钉长度变化显著(平均 8.0mm,P<0.05),三射线软骨开放也有显著变化(平均 7.7mm,P<0.05)。在两个队列中,后倾角度和关节突-转子距离均无变化,表明无论是治疗组还是预防性组均无滑脱节进展,相对于大转子,对近端骨骺生长的影响最小。

结论

在患有 SCFE 的年轻患者中,生长中的螺钉结构可以阻止滑脱节进展,同时允许股骨近端生长。预防性固定时,骨的生长更好。需要扩大治疗性 SCFE 的结果,以证明显著生长的临床有意义的截止值,但三射线软骨开放的 SCFE 患者明显比闭合的患者重塑更多。

证据水平

III 级回顾性比较研究。

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