与汉赛巴尔通体感染相关的视网膜中央静脉阻塞
Central retinal vein occlusion associated with Bartonella henselae infection.
作者信息
Bellur Sunil, Ali Amir, Nguyen Nam V, Fernandes Joshua K, Kodati Shilpa
机构信息
National Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N248, Bethesda, Maryland, 20892, USA.
University of Texas Medical Branch, Galveston, Texas, USA.
出版信息
J Ophthalmic Inflamm Infect. 2023 Mar 28;13(1):14. doi: 10.1186/s12348-023-00334-5.
PURPOSE
To report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection.
OBSERVATION
A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms but reported prior exposure to fleas. Best corrected visual acuity (BCVA) was 20/400 in the left eye. Clinical examination revealed a CRVO with atypical features including significant peripapillary exudates and peripheral vascular sheathing. Laboratory testing revealed elevated B. henselae IgG titers (1:512) with no abnormalities on hypercoagulability testing. The patient was treated with doxycycline and aflibercept with an excellent clinical response and improvement in BCVA to 20/25 in the left eye two months later.
CONCLUSION
CRVO is a rare but sight-threatening complication of ocular bartonellosis and can be the presenting sign of infection, even in the absence of cat exposure or prodromal symptoms.
目的
报告一例以视网膜中央静脉阻塞（CRVO）为眼部汉赛巴尔通体（B. henselae）感染初始体征的临床特征及治疗过程。
观察
一名36岁男性因单眼视力丧失接受评估。他否认前驱症状，但报告曾接触过跳蚤。左眼最佳矫正视力（BCVA）为20/400。临床检查发现CRVO伴有非典型特征，包括显著的视乳头周围渗出物和周边血管鞘膜。实验室检测显示汉赛巴尔通体IgG滴度升高（1:512），高凝状态检测无异常。患者接受强力霉素和阿柏西普治疗，临床反应良好，两个月后左眼BCVA改善至20/25。
结论
CRVO是眼部巴尔通体病罕见但威胁视力的并发症，即使在没有接触猫或前驱症状的情况下，也可能是感染的首发体征。
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