Rosa Sofia, Silvestre-Ferreira Ana C, Sargo Roberto, Silva Filipe, Queiroga Felisbina Luísa
School of Life and Environmental Sciences (ECVA), University of Trás-os-Montes and Alto Douro (UTAD), Quinta dos Prados, 5001-801 Vila Real, Portugal.
Department of Veterinary Science, School of Agrarian and Veterinary Sciences (ECAV), University of Trás-os-Montes and Alto Douro (UTAD), Quinta dos Prados, 5001-801 Vila Real, Portugal.
Animals (Basel). 2023 Mar 10;13(6):1009. doi: 10.3390/ani13061009.
The Western European hedgehog ( can work as a bioindicator of environmental pollution and be a host for multiple zoonotic agents, making it relevant in terms of One Health studies. It is essential to deepen the knowledge on this species and calculate reference intervals (RIs) for the usual hematological and biochemical parameters. For this retrospective study (2017-2022), the archives of the Clinical Pathology Laboratory (LPC) of University of Trás-os-Montes and Alto Douro (UTAD) Veterinary Teaching Hospital were analyzed. Data of hematology, clinical biochemistry, and protein electrophoresis from 37 healthy hedgehogs of the Wild Animal Rehabilitation Center at UTAD, Northern Portugal, were included. It was possible to calculate RIs for almost all of the variables in the study, using Reference Value Advisor V2.1. Moreover, sex and age effects were investigated: alkaline phosphatase ( = 0.012, higher in males); total proteins ( = 0.034, higher in adults); mean cell volume ( = 0.007) and mean corpuscular hemoglobin ( = 0.010) (both higher in juveniles); and red blood cell distribution width ( = 0.021, higher in adults). Our study allowed for the first time to define RIs for a population of hedgehogs in Portugal, having a potentially relevant impact on species conservation and in the human-animal health interface.
西欧刺猬可作为环境污染的生物指示物，也是多种人畜共患病原体的宿主，因此在“同一健康”研究方面具有重要意义。加深对该物种的了解并计算常见血液学和生化参数的参考区间至关重要。在这项回顾性研究（2017 - 2022年）中，分析了特拉索斯 - 蒙特斯和阿尔托杜罗大学（UTAD）兽医教学医院临床病理实验室（LPC）的档案。纳入了来自葡萄牙北部UTAD野生动物康复中心的37只健康刺猬的血液学、临床生化和蛋白质电泳数据。使用参考值顾问V2.1可以计算出研究中几乎所有变量的参考区间。此外，还研究了性别和年龄的影响：碱性磷酸酶（P = 0.012，雄性较高）；总蛋白（P = 0.034，成年刺猬较高）；平均细胞体积（P = 0.007）和平均红细胞血红蛋白含量（P = 0.010）（两者在幼年刺猬中较高）；以及红细胞分布宽度（P = 0.021，成年刺猬较高）。我们的研究首次为葡萄牙的刺猬种群定义了参考区间，这可能对物种保护以及人类与动物健康的界面产生潜在的重要影响。
