用于射血分数保留的心力衰竭的离心式左心房减压泵的血流动力学评估
Hemodynamic Evaluation of a Centrifugal Left Atrial Decompression Pump for Heart Failure with Preserved Ejection Fraction.
作者信息
Abbasnezhad Navideh, Specklin Mathieu, Bakir Farid, Leprince Pascal, Danial Pichoy
机构信息
Arts et Métiers Institute of Technology, CNAM, LIFSE, HESAM University, F-75013 Paris, France.
Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne University, F-75013 Paris, France.
出版信息
Bioengineering (Basel). 2023 Mar 17;10(3):366. doi: 10.3390/bioengineering10030366.
This article discusses a new continuous flow mini pump that has been developed to improve symptoms and prognosis in patients with Heart Failure with Preserved Ejection Fraction (HFpEF), for which there are currently no established treatments. The pump is designed to discharge a reduced percentage of blood volume from the left atrium to the subclavian artery, clamped at the bifurcation with the aortic arch. The overall specifications, design parameters, and hemodynamics of this new device are discussed, along with data from in vitro circulation loop tests and numerical simulations. The article also compares the results for two configurations of the pump with respect to key indicators of hemocompatibility used in blood pump development.
本文讨论了一种新开发的连续流微型泵，该泵旨在改善射血分数保留的心力衰竭（HFpEF）患者的症状和预后，目前针对HFpEF尚无既定的治疗方法。该泵的设计目的是将左心房中减少比例的血容量排放到锁骨下动脉，锁骨下动脉在与主动脉弓的分叉处被夹住。文中讨论了这种新装置的总体规格、设计参数和血液动力学，以及体外循环回路测试和数值模拟的数据。本文还比较了该泵的两种配置在血泵开发中使用的血液相容性关键指标方面的结果。
Zotero 插件