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性别对失眠的影响。

Impact of Gender on Insomnia.

作者信息

Boer Jolijn, Höhle Nadya, Rosenblum Lisa, Fietze Ingo

机构信息

Department of Internal Medicine and Dermatology, Interdisciplinary Center of Sleep Medicine, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.

出版信息

Brain Sci. 2023 Mar 12;13(3):480. doi: 10.3390/brainsci13030480.

Abstract

There is a distinct preponderance of female insomniacs when compared to male insomniacs. The aim of this study was to examine possible gender differences in the causes for insomnia, and the phenotypes of insomnia, and to investigate whether gender-specific insomnia diagnosis and treatment could be relevant in clinical practice. Data were collected from 121 insomniac patients by a medical specialist in the framework of normal clinical practice in Germany. The data consist of the patient's medical history and various sleep-related patient questionnaires. Data from both genders were tested for independence using chi-square tests and Mann-Whitney U tests. We found a correlation between the gender of the patient and insomnia phenotypes in several aspects: concomitant lipometabolic disorders, diabetes mellitus, and high BMIs are more common in male insomniacs ( < 0.05). Frequency of insomnia occurrence in certain age groups, insomnia severity, distribution of SOI (sleep onset insomnia), SMI (sleep maintenance insomnia) and combined SOI + SMI, sleep duration, the time needed to seek medical consultation, trying out sleep-inducing drugs/techniques and the trigger, etiology and familial predisposition of the insomniac disorder were independent of the patient's gender. We would like to re-evaluate the results with a larger number of patients in a further study.

摘要

与男性失眠症患者相比,女性失眠症患者明显占多数。本研究的目的是探讨失眠原因及失眠表型中可能存在的性别差异,并调查针对特定性别的失眠诊断和治疗在临床实践中是否具有相关性。在德国正常临床实践框架内,由一名医学专家从121名失眠症患者处收集数据。数据包括患者的病史和各种与睡眠相关的患者问卷。使用卡方检验和曼-惠特尼U检验对两性数据进行独立性检验。我们在几个方面发现了患者性别与失眠表型之间的相关性:伴有脂代谢紊乱、糖尿病和高体重指数在男性失眠症患者中更为常见(<0.05)。特定年龄组失眠症的发生频率、失眠严重程度、入睡失眠(SOI)、睡眠维持失眠(SMI)以及联合的SOI+SMI的分布、睡眠时间、寻求医疗咨询所需时间、尝试助眠药物/技术以及失眠症的触发因素、病因和家族易感性与患者性别无关。我们希望在进一步的研究中用更多患者重新评估这些结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7062/10046211/7d6d10191358/brainsci-13-00480-g001.jpg

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