Möhler Ricarda, Jenetzky Ekkehart, Schwarz Silke, Gwiasda Moritz, Rathjens Larisa, Martin David D
Faculty of Health, School of Medicine, 58448 Witten, Germany.
Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center of the Johannes-Gutenberg-University Mainz, 55131 Mainz, Germany.
Children (Basel). 2023 Feb 22;10(3):419. doi: 10.3390/children10030419.
Febrile infections are common in childhood. Children can be infected with SARS-CoV-2, but their course is milder than in adults. So far, a comparison between febrile infections with a positive or negative Corona test with the Omicron variant is missing. The data used are from the FeverApp registry, which collects parent-reported data on febrile infections in children and informs about fever management. A comparison of symptomatic differences between episodes with a positive or negative Corona test was performed using Χ-tests. During the Omicron wave, reported tests doubled and positive test results nearly 12-folded. In episodes with positive Corona saliva tests, more cough, fatigue, disturbed smell/taste, limb pain, sore throat, signs of serious sickness, and touch sensitivity were reported. Children with a negative Corona test show more tonsillitis, teething, any pain symptoms, earaches, and rashes. Thus, there are some significant differences between febrile infections with a positive or negative Corona test, but symptoms are present on both sides. The omicron variant seems to be more infectious than the alpha or delta variants in children, but the symptoms remain mild and do not differ much from other febrile infections.
发热性感染在儿童时期很常见。儿童可能感染新冠病毒，但他们的病程比成人更轻。到目前为止，缺乏对奥密克戎变异株新冠检测呈阳性或阴性的发热性感染之间的比较。所使用的数据来自FeverApp登记处，该登记处收集家长报告的儿童发热性感染数据并提供发热管理信息。使用卡方检验对新冠检测呈阳性或阴性的发作之间的症状差异进行了比较。在奥密克戎毒株流行期间，报告的检测数量翻倍，阳性检测结果增加了近12倍。在新冠唾液检测呈阳性的发作中，报告有更多咳嗽、疲劳、嗅觉/味觉障碍、肢体疼痛、喉咙痛、重病迹象和触觉敏感。新冠检测呈阴性的儿童表现出更多扁桃体炎、出牙、任何疼痛症状、耳痛和皮疹。因此，新冠检测呈阳性或阴性的发热性感染之间存在一些显著差异，但两侧都有症状。奥密克戎变异株在儿童中似乎比阿尔法或德尔塔变异株更具传染性，但症状仍然较轻，与其他发热性感染没有太大差异。
