Ghouri Syed Imran, Mustafa Fuad, Kanbar Ahad, Al Jogol Hisham, Shunni Adam, Almadani Ammar, Abdurraheim Nuri, Goel Atirek Pratap, Abdelrahman Husham, Babikir Elhadi, Ramzee Ahmed F, Ahmed Khalid, Alhardallo Mutaz, Asim Mohammad, Al-Thani Hassan, El-Menyar Ayman
Department of Surgery, Orthopedic Surgery, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar.
Trauma Surgery Section, Hamad General Hospital (HGH), Doha P.O. Box 3050, Qatar.
Diagnostics (Basel). 2023 Mar 17;13(6):1147. doi: 10.3390/diagnostics13061147.
Femur shaft factures (FSF) are common injuries following high-energy mechanisms mainly involving motor vehicle crashes (MVC). We evaluated the timings of nailing management and analyzed the pattern of fracture union and outcome in a level 1 trauma center.
This was a retrospective observational study of all the admitted trauma patients who sustained femoral fractures between January 2016 and September 2020. Data were analyzed and compared based on time to Intramedullary Nailing (IMN) (<12 h, 12-24 h and >24 h) and outcomes of FSF (union, delayed union and nonunion).
A total of 668 eligible patients were included in the study, of which the majority were males (90.9%) with a mean age of 34.5 ± 15.8, and 54% of the injuries were due to MVCs. The chest (35.8%) was the most commonly associated injured body region, followed by the pelvis (25.9%) and spine (25.4%). Most of femur fractures (93.3%) were unilateral, and 84.4% were closed fractures. The complete union of fractures was observed in 76.8% of cases, whereas only 4.2% and 3.3% cases had delayed union and nonunion, respectively, on the clinical follow-up. Patients in the delayed IMN (>24 h) were severely injured, had bilateral femur fracture ( = 0.001) and had higher rate of external fixation, blood transfusion, pulmonary complications and prolonged hospitalization. Non-union proportion was greater in those who had IMN <24 h, whereas a delayed union was greater in IMN done after 24 h ( = 0.5). Those with a nonunion femur fracture were more likely to have bilateral fracture ( = 0.003), frequently had retrograde nailing ( = 0.01), and high-grade femur fracture (AO type C; = 0.04).
This study showed that femur fracture is not uncommon (8.9%), which is manifested with the variety of clinical characteristics, depending on the mechanism, management and outcome in our center. Bilateral fracture, retrograde nailing and AO classification type C were the significant risk factors of non-union in patients with diaphyseal fractures. The timing of IMN has an impact on the fracture union; however, it is not a statistically significant difference. Therefore, the treating physicians should consider the potential risk factors for a better outcome by careful selection of treatment in sub-groups of patients.
股骨干骨折(FSF)是高能机制损伤后的常见骨折,主要由机动车碰撞(MVC)导致。我们在一级创伤中心评估了髓内钉治疗的时机,并分析了骨折愈合模式及结果。
这是一项对2016年1月至2020年9月间所有因股骨骨折入院的创伤患者进行的回顾性观察研究。根据髓内钉置入时间(<12小时、12 - 24小时和>24小时)以及股骨干骨折的结果(愈合、延迟愈合和不愈合)对数据进行分析和比较。
本研究共纳入668例符合条件的患者,其中大多数为男性(90.9%),平均年龄34.5±15.8岁,54%的损伤由机动车碰撞所致。胸部(35.8%)是最常合并损伤的身体部位,其次是骨盆(25.9%)和脊柱(25.4%)。大多数股骨干骨折(93.3%)为单侧,84.4%为闭合性骨折。在临床随访中,76.8%的病例骨折完全愈合,而分别只有4.2%和3.3%的病例出现延迟愈合和不愈合。延迟髓内钉置入组(>24小时)的患者损伤严重,有双侧股骨干骨折(P = 0.001),且外固定、输血、肺部并发症发生率及住院时间延长的比例更高。髓内钉置入时间<24小时的患者不愈合比例更高,而髓内钉置入时间在24小时后延迟愈合比例更高(P = 0.5)。股骨干骨折不愈合的患者更易出现双侧骨折(P = 0.003),常采用逆行髓内钉固定(P = 0.01),且为高等级股骨干骨折(AO C型;P = 0.04)。
本研究表明股骨干骨折并不少见(8.9%),根据我们中心的损伤机制、治疗方法及结果,其具有多种临床特征。双侧骨折、逆行髓内钉固定及AO分类C型是骨干骨折患者不愈合的重要危险因素。髓内钉置入时机对骨折愈合有影响,但无统计学显著差异。因此,治疗医师应通过仔细选择亚组患者的治疗方法来考虑潜在危险因素以获得更好的治疗效果。