Lokich J, Zipoli T, Greene R, Paul S, Sonnenborn H, Moore C
Cancer Treat Rep. 1986 Apr;70(4):523-4.
Protracted, 24-hour, continuous-infusion cisplatin at a dose rate of 5 mg/m2/day was administered to 25 patients with advanced measurable colorectal cancer. All patients had previously received 5-FU administered on the same schedule. Sixteen patients received the infusion for greater than or equal to 14 days and were considered evaluable for response assessment. No patient achieved a response.
对25例晚期可测量的结直肠癌患者给予持续24小时的顺铂持续静脉输注，剂量率为5mg/m²/天。所有患者此前均按相同方案接受过5-氟尿嘧啶治疗。16例患者接受输注≥14天，并被认为可进行疗效评估。无患者获得缓解。
