血液透析患者下肢外周动脉疾病与轻度认知障碍的关系
Relationship between Lower Extremity Peripheral Arterial Disease and Mild Cognitive Impairment in Hemodialysis Patients.
作者信息
Nishimura Akinori, Hidaka Sumi, Kawaguchi Takayuki, Watanabe Aki, Mochida Yasuhiro, Ishioka Kunihiro, Mwanatanbwe Milanga, Ohtake Takayasu, Kobayashi Shuzo
机构信息
Rehabilitation Unit, Shonan Kamakura General Hospital, Okamoto 1370_1, Kamakura 247-8533, Japan.
Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kamakura 247-8533, Japan.
出版信息
J Clin Med. 2023 Mar 9;12(6):2145. doi: 10.3390/jcm12062145.
The link between arterial stiffness and mild cognitive impairment (MCI) in patients on hemodialysis (HD) has been receiving increased attention. The purpose of this study was to investigate the relationship between cognitive function and ankle brachial index (ABI) and toe brachial index (TBI) values in patients on hemodialysis. Of the 100 participants (mean age: 67.9 years; average history of hemodialysis: 7.3 years). Of these, 46.0% had MCI. The MoCA-J scores were significantly higher in the ABI ≥ 1.06 group. However, the MoCA-J scores divided into the two groups according to the TBI cutoff value were not significantly different. In a multiple regression model with the MoCA-J scores as the objective variable, the ABI was a significantly associated factor. This study indicates that a low ABI might be associated with MCI.
血液透析（HD）患者的动脉僵硬度与轻度认知障碍（MCI）之间的联系日益受到关注。本研究旨在探讨血液透析患者认知功能与踝臂指数（ABI）和趾臂指数（TBI）值之间的关系。100名参与者（平均年龄：67.9岁；平均血液透析史：7.3年）。其中，46.0%患有MCI。ABI≥1.06组的蒙特利尔认知评估量表日本版（MoCA-J）得分显著更高。然而，根据TBI临界值分为两组的MoCA-J得分并无显著差异。在以MoCA-J得分为目标变量的多元回归模型中，ABI是一个显著相关因素。本研究表明，低ABI可能与MCI有关。
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