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传统中医运动对慢性心力衰竭患者的影响(TCE-HF):一项系统评价和荟萃分析

Effect of Traditional Chinese Exercises on Patients with Chronic Heart Failure (TCE-HF): A Systematic Review and Meta-Analysis.

作者信息

Bao Qinyi, Lei Shuxin, Guo Shitian, Wang Zhuo, Yu Jiaye, You Yayu, Zhang Ning, Xie Xiaojie

机构信息

Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

Department of Cardiology, First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

出版信息

J Clin Med. 2023 Mar 9;12(6):2150. doi: 10.3390/jcm12062150.

Abstract

Exercise-based cardiac rehabilitation is safe and effective for chronic heart failure (CHF) patients. The present study aimed to investigate the effects of traditional Chinese exercise (TCE) on patients with CHF and the impact of exercise types and duration. Evaluation of randomized controlled trials (RCTs) of TCE in patients with CHF published since 1997 from PubMed, Embase, Web of Science, the Cochrane Library, Chongqing VIP, Wanfang Databases, and the China National Knowledge was performed. A total of 41 RCTs, including 3209 patients with CHF, were included. It showed that TCE significantly increased 6-min walk distance (6MWD) [mean difference (MD) = 72.82 m, < 0.001] and left ventricular ejection fraction (MD = 5.09%, < 0.001), whereas reduced B-type natriuretic peptide (BNP) (MD = -56.80 pg/mL, < 0.001), N-terminal pro-BNP (MD = -174.94 pg/mL, < 0.05), and Minnesota Living with Heart Failure Questionnaire scores (MD = -11.31, < 0.001). However, no significant difference was found in the effects of TCE on peak oxygen consumption. The increase in TCE weekly duration and program duration significantly improved 6MWD (MD = 71.91 m, < 0.001; MD = 74.11 m, < 0.001). The combination of TCE and conventional aerobic exercise significantly improved 6MWD (MD = 19.86 m, < 0.005). TCE improves exercise capacity, cardiac function, and quality of life in patients with CHF, which might be an optimal and available pattern of exercise-based cardiac rehabilitation.

摘要

基于运动的心脏康复对慢性心力衰竭(CHF)患者是安全有效的。本研究旨在探讨传统中式运动(TCE)对CHF患者的影响以及运动类型和时长的作用。对自1997年以来在PubMed、Embase、科学网、考克兰图书馆、重庆维普、万方数据库和中国知网发表的关于TCE治疗CHF患者的随机对照试验(RCT)进行了评估。共纳入41项RCT,包括3209例CHF患者。结果显示,TCE显著增加了6分钟步行距离(6MWD)[平均差(MD)=72.82米,<0.001]和左心室射血分数(MD = 5.09%,<0.001),而降低了B型利钠肽(BNP)(MD = -56.80 pg/mL,<0.001)、N末端B型利钠肽原(MD = -174.94 pg/mL,<0.05)以及明尼苏达心力衰竭生活问卷评分(MD = -11.31,<0.001)。然而,TCE对峰值耗氧量的影响未发现显著差异。TCE每周时长和项目时长的增加显著改善了6MWD(MD = 71.91米,<0.001;MD = 74.11米,<0.001)。TCE与传统有氧运动相结合显著改善了6MWD(MD = 19.86米,<0.005)。TCE可改善CHF患者的运动能力、心脏功能和生活质量,这可能是基于运动的心脏康复的一种最佳且可行的模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e6/10054845/b1102b736d83/jcm-12-02150-g001.jpg

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