Landon G C, Galante J O, Maley M M
Clin Orthop Relat Res. 1986 Apr(205):49-57.
Extensive animal experimentation has proven porous titanium fiber composite to be an effective interface for direct attachment of prosthetic devices via bone ingrowth. Titanium has demonstrated excellent biocompatibility in long-term primate experiments. Utilizing this technology, a cementless total knee system has been developed. A pilot study of 34 knees demonstrated the feasibility of anchoring the tibial component without cement. A totally cementless unconstrained total knee replacement was designed with porous titanium fiber composite interfaces. Retention of the posterior cruciate ligament was an essential part of the design. A large range of sizes was chosen to allow precise fitting of individual patients with distribution of load over the maximum surface available. Early clinical results have been very encouraging. Patients have achieved excellent pain relief, rapid return of function, and range of motion exceeding previous designs.
大量动物实验已证明,多孔钛纤维复合材料是通过骨长入直接连接假体装置的有效界面。在长期灵长类动物实验中,钛已显示出优异的生物相容性。利用这项技术,已开发出一种无骨水泥全膝关节系统。一项针对34个膝关节的初步研究证明了不使用骨水泥固定胫骨部件的可行性。设计了一种完全无骨水泥的非限制性全膝关节置换术,采用多孔钛纤维复合材料界面。保留后交叉韧带是该设计的一个重要部分。选择了大范围的尺寸,以便能精确适配个体患者,并使负荷分布在最大可用表面上。早期临床结果非常令人鼓舞。患者实现了极佳的疼痛缓解、功能快速恢复,且活动范围超过了以往的设计。